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MEPRON
Fungal infections
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Drug Name:

MEPRON Rx

Generic Name and Formulations:
Atovaquone 750mg/5mL; susp; citrus flavor.

Company:
GlaxoSmithKline

Therapeutic Use:

Indications for MEPRON:

Treatment of mild to moderate Pneumocystis carinii pneumonia (PCP) in patients intolerant to trimethoprim/sulfamethoxazole (TMP/SMX). Prevention of PCP in patients intolerant to TMP/SMX.

Adult:

Take with food. Treatment: 750mg twice daily for 21 days. Prophylaxis: 1500mg once daily.

Children:

See full labeling.

Warnings/Precautions:

GI disorders or inability to take with food. Monitor in severe hepatic impairment. Elderly. Pregnancy (Cat.C). Nursing mothers.

Interactions:

Antagonized by rifampin. Caution with other highly protein-bound drugs.

Pharmacological Class:

Naphthoquinone.

Adverse Reactions:

Rash, headache, GI upset, dyspnea, cough, rhinitis, infection, fever, elevated liver enzymes, insomnia, asthenia, oral moniliasis, pruritus, sinusitis, anorexia, depression, myalgia, pancreatitis, thrombocytopenia, allergic reactions.

How Supplied:

Susp—210mL

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