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IPOL
Vaccines
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Drug Name:

IPOL Rx

Generic Name and Formulations:
Trivalent poliovirus vaccine; inactivated; whole virus grown in monkey kidney cells; IM or SC inj.

Company:
Sanofi Pasteur, Inc.

Therapeutic Use:

Indications for IPOL:

Poliomyelitis immunization (virus Types 1, 2, and 3).

Adult:

Inject IM or SC in deltoid area. Each dose is 0.5mL. Previously unvaccinated: Two doses at a 1–2 month interval and a third dose 6–12 months later. Incompletely vaccinated: give 1–2 doses to complete series. Completely vaccinated: may give booster dose.

Children:

Inject IM or SC in midlateral thigh. Each dose is 0.5mL. Under 6 wks: not recommended. Full IPV schedule: One dose at 2 months, 4 months, 6–18 months, and 4–6 years of age. Sequential schedule with oral polio vaccine (OPV) (do not use OPV for immunocompromised patients or patients with immunocompromised household contacts): One dose of IPOL at 2 months and at 4 months of age, then 1 dose of OPV at 12–18 months and 1 dose of OPV at 4–6 years of age.

Contraindications:

Hypersensitivity to neomycin, streptomycin, or polymyxin B. May defer in acute febrile illness.

Warnings/Precautions:

Have epinephrine inj (1:1000) available. Immunodeficiency. Pregnancy (Cat.C). Nursing mothers.

Interactions:

Immunosuppressants: may get suboptimal response.

Pharmacological Class:

IPV.

Adverse Reactions:

Local irritation, fever, sleepiness, fussiness, decreased appetite.

How Supplied:

Syringe 0.5mL (w. needle)—1, 10; Multidose vial (10 doses)—1

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