Hydrocodone Bitartrate/Homatropine Methylbromide Tablets CII
Generic Name and Formulations:
Hydrocodone bitartrate 5mg, homatropine methylbromide 1.5mg; tabs.
Various generic manufacturers
Indications for Hydrocodone Bitartrate/Homatropine Methylbromide Tablets:
≥12yrs: 1 tab every 4–6hrs as needed; max 6 tabs/24hrs.
<6yrs: not recommended. 6–11yrs: ½ tab every 4–6hrs as needed; max 3 tabs/24hrs.
Risks from concomitant benzodiazepines or other CNS depressants (see Interactions). Risk of life-threatening respiratory depression (esp. in children). Abuse potential (monitor). Head injury, other intracranial lesions or pre-existing increase in intracranial pressure. Acute abdomen. Hypothyroidism. Addison's disease. Prostatic hypertrophy. Urethral stricture. Asthma. Narrow-angle glaucoma. Severe hepatic or renal impairment. Elderly. Debilitated. Labor & delivery. Pregnancy (Cat.C). Nursing mothers: not recommended.
Increased risk of respiratory depression, sedation with benzodiazepines or other CNS depressants (eg, opioids, antihistamines, antipsychotics, anxiolytics, alcohol); avoid. May affect or be affected by MAOIs, TCAs.
Respiratory depression, drowsiness, hypertension, orthostatic hypotension, palpitations, anticholinergic effects, sedation, anxiety, nausea, rash, pruritus.
Formerly known under the brand name Hycodan.
Sign Up for Free e-newsletters
Psychiatry Advisor Articles
- Adjunctive Therapies for Bipolar Disorder Show Promise, Need More Evidence
- Improving Performance of Everyday Activities Is Critical in Schizophrenia
- Predicting Treatment-Emergent Mania to Tailor Pharmacotherapy in Bipolar Disorder
- Analysis Finds Lithium Maintenance Most Effective as Monotherapy in Bipolar Disorder
- Web-Based Intervention Targets Parental Behaviors That May Affect Adolescent Anxiety, Depression
- The Way to the Head May Be Through the Gut: Probiotics for Depression
- Suicide-Screening Toolkit Can Help Identify Youths at High Risk for Suicide
- Agoraphobia: An Evolving Understanding of Definitions and Treatment
- Parental Pressure to Diet Linked With Long-term Harm in Adolescents
- Does Access to Medical Cannabis Reduce Risk for Opioid Abuse?
- Examining Rates of Long-term Opioid Use in Youth With Psychiatric Disorders
- Mortality Rates for Substance Use Disorders, Intentional Injuries Vary Widely By Country
- Facial Emotion Recognition Differentiates Behavioral Variant Frontotemporal Dementia From MDD
- The Challenge of Helping Uninsured Patients While Protecting Practice Finances
- Antidepressants Increase Seizure Risk in Youth and Severely Depressed