Individuals with primary progressive aphasia associated with Alzheimer disease have longitudinally preserved episodic memory.
Despite the many loci associated with late-onset Alzheimer disease, researchers are still short of a robust, unified method of risk stratification based on genome variations due to the clinical heterogeneity and polygenic nature of the disease.
This study looks at how the lack of awareness (anosognosia) of memory impairment evolves in the trajectory of Alzheimer disease.
Amyloid-β (Aβ) deposition, a feature of Alzheimer disease, may be promoted by external factors. The researchers of this study examined the association between the likelihood of amyloid positron emission tomography (PET) scan positivity and ambient air quality in individuals with cognitive impairment.
Researchers analyzed data from a nationally representative study of older non-Hispanic Black and White adults to evaluate progress toward reducing racial disparities regarding dementia.
Late-life exposure to particulate matter with aerodynamic diameter <2.5 µm is associated with Alzheimer disease (AD) pattern similarity scores among women, corresponding to an increase in AD risk.
Test from C2N Diagnostics is meant for people 60 years and older who have cognitive issues and are being assessed for Alzheimer disease
ApoE4 genotype, anxiety, and lower hippocampal and entorhinal cortex volumes are associated with an elevated progression rate from mild cognitive impairment to Alzheimer disease.
Reduced slow-wave activity during non-rapid eye movement sleep and low sleep efficiency, both of which sleep assessments can measure, may be part of biomarkers that forecast the rate of cortical β-amyloid deposition in the brain.
This study examines whether the genetic variation near the apolipoprotein E gene (APOE) is associated with risk of Alzheimer disease independently of the ε2/ε3/ε4 genotype.