Generic Name and Formulations:
Methenamine hippurate 1 g; tabs; contains tartrazine.
Indications for HIPREX:
Prophylaxis and suppression of recurrent UTIs.
1 g twice daily.
<6 years: not recommended. ≥6 years: 0.5–1 g twice daily.
Renal or hepatic insufficiency. Severe dehydration. As sole therapy in infections with systemic involvement.
Maintain acid urine. Monitor therapy and liver function with repeated urine cultures. Aspirin allergy. Pregnancy.
Sulfonamides precipitate with formaldehyde in urine; avoid concomitant use.
Nausea, dysuria, rash, bladder irritation, albuminuria, hematuria, elevated transaminases.
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