Gene-Environment Interaction

Genomic Medicine and the Future of Health Care

Genomic Medicine and the Future of Health Care

By

Embracing all the myriad variations of the human genome should, in theory, lead to rewards that all can share.

Interaction of Proline and COMT Genotype Influences Negative Symptoms in Schizophrenia & Bipolar Disorder

Interaction of Proline and COMT Genotype Influences Negative Symptoms in Schizophrenia & Bipolar Disorder

By

The authors explored whether valproate (VPA) treatment effects vary by catechol-O-methyltransferase (COMT) genotype.

Association Between Polymorphisms in the FKBP5 Gene and MDD

Association Between Polymorphisms in the FKBP5 Gene and MDD

By

It is hypothesized that multiple single nucleotide polymorphisms (SNPs) work together to influence risk of complex neuropsychiatric disorders such as depression.

Evidence for a Role of Neuropeptide Y Receptor Variant in Depression

Evidence for a Role of Neuropeptide Y Receptor Variant in Depression

By

Genetic variation can increase the predisposition to major depressive disorder.

Comorbid Chronic Pain and Depression: Gene x Environment Interaction

Comorbid Chronic Pain and Depression: Gene x Environment Interaction

By

Genetic factors and the environment patients share with their partner or spouse may determine their risk of developing chronic pain and help explain the association between chronic pain and depression.

Female-specific CBT for Women Diagnosed With Alcohol Use Disorder

Female-specific CBT for Women Diagnosed With Alcohol Use Disorder

By

Compared with men, women diagnosed with AUD have higher rates of premature death due to alcohol abuse.

Patterns and Strength of Familial Aggregation of ADHD

Patterns and Strength of Familial Aggregation of ADHD

By

Investigators used decomposition methods to examine the relative importance of genetic and environmental components to the burden of ADHD.

Interactive Effects of Genotype and Childhood Adversity on Alcohol Consumption

Interactive Effects of Genotype and Childhood Adversity on Alcohol Consumption

By

Early life trauma interacts with FKBP5 genotype to predict heavy alcohol consumption in college students.

How to Improve Interpretability of Epigenomic Studies

How to Improve Interpretability of Epigenomic Studies

By

Appropriate study planning from the outset is one step that can help improve interpretability.

Urinary Biomarker of Parkinson Disease Identified

Urinary Biomarker of Parkinson Disease Identified

By

To date, there are no validated biomarkers to independently assess Parkinson Disease diagnosis and prognosis, or to measure disease severity.

Epigenetic Alterations Reversible Before Transmission to Offspring

Epigenetic Alterations Reversible Before Transmission to Offspring

By

Preventing Transgenerational Effects of Paternal Trauma

Link Between Genetic Variation, Lifetime Cannabis Use Found

Link Between Genetic Variation, Lifetime Cannabis Use Found

By

Approximately 30% of users exhibit signs of marijuana abuse or dependence.

Intergenerational Transmission of Stress Vulnerability and Resilience Following Trauma

Intergenerational Transmission of Stress Vulnerability and Resilience Following Trauma

By

Extreme trauma affects FKBP5 methylation in survivors of the Holocaust as well as in their offspring.

Sign Up for Free e-newsletters