FEMHRT 0.5/2.5 Rx
Generic Name and Formulations:
Norethindrone acetate 0.5mg, ethinyl estradiol 2.5mcg; tabs.
Indications for FEMHRT 0.5/2.5:
In women with an intact uterus: moderate to severe vasomotor symptoms associated with menopause; osteoporosis prevention.
1 tab daily. Reevaluate periodically.
Breast or estrogen-dependent carcinoma. Undiagnosed abnormal genital bleeding. Thrombophlebitis. Thromboembolic disorders. Missed abortion. Pregnancy (Cat.X).
Gallbladder disease. Hypercalcemia in breast cancer or bone metastases. Conditions aggravated by fluid retention. Hepatic impairment. Hypercoagulability. Familial hyperlipoproteinemia. Depression. Do initial complete physical exam and repeat at least yearly (include BP, PAP smear, mammogram). Discontinue if cardiovascular events, jaundice, visual abnormalities or migraine occurs and at least 2 weeks before surgery associated with increased risk of thromboembolism. Nursing mothers.
May be antagonized by rifampin, troglitazone, anticonvulsants. May antagonize temazepam, morphine, clofibrate. May be potentiated by Vit. C, acetaminophen, atorvastatin. Monitor theophylline, cyclosporine. May interfere with lab tests; see literature.
Progestin + estrogen.
GI upset, constipation, headache, edema, depression, nervousness, mastodynia, intolerance to contact lenses, glucose intolerance, changes in serum lipids; others.
Psychiatry Advisor Articles
- ADHD, Comorbid Bipolar Disorder Share Similar Neurocognitive Profiles
- Anxiety Prevention Interventions: How Effective Are They?
- ACOG Update: Marijuana Use Discouraged During Pregnancy, Breastfeeding
- Depression Profiles in Patients With Type 1 Diabetes vs Type 2 Diabetes
- No Evidence of Personality Changes Prior to Developing Cognitive Impairment, Dementia
- Suicidal Behavior, Thoughts Associated With Perfectionist Tendencies
- Physicians Spend Nearly 6 Hours on EHR Tasks Per Day
- CBT, Acceptance Commitment Therapy Helpful for Those With Chronic Pain
- Depression Reduced by Social Belonging, Feelings of Inclusion
- Sleep Disturbance May Be Causal Factor in Psychotic Experiences
- Is Hypertension Linked to an Increased Risk of Dementia?
- Continuing Research, Emerging Treatments Hold Promise for Treating Anorexia Nervosa
- Maternal Glucocorticoid Exposure Not Associated With ADHD in Offspring
- Ketamine Not Associated With PTSD Development in Military Trauma Setting
- Content, Quality Issues for Both Paper-Based and Electronic Health Records