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Felodipine
Hypertension
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Drug Name:

Felodipine Rx

Generic Name and Formulations:
Felodipine 2.5mg, 5mg, 10mg; ext rel tabs.

Company:
Various generic manufacturers

Therapeutic Use:

Indications for Felodipine:

Hypertension.

Adult:

Take without food or with a light meal. Do not crush or chew. Initially 5mg once daily. Range 2.5–10mg once daily. Adjust at 2 week intervals; max 10mg daily. Elderly or hepatic dysfunction: initially 2.5mg once daily.

Children:

Not recommended.

Warnings/Precautions:

Heart failure. Hepatic impairment. Maintain good dental hygiene. Elderly. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

May increase metoprolol, tacrolimus levels. Potentiated by cimetidine. Increased bioavailability with grapefruit juice. Levels decreased with long-term anticonvulsants (eg, carbamazepine, phenytoin, phenobarbital), consider alternate antihypertensive therapy.

Pharmacological Class:

Calcium channel blocker (CCB) (dihydropyridine).

Adverse Reactions:

Peripheral edema, headache, flushing, dizziness, respiratory symptoms, weakness, cough, GI upset, gynecomastia; hypotension, tachycardia, syncope, MI, angina, gingival hyperplasia (rare).

Note:

Formerly known under the brand name Plendil.

How Supplied:

Contact supplier.

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