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EXONDYS 51
Miscellaneous musculoskeletal disorders
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Drug Name:

EXONDYS 51 Rx

Generic Name and Formulations:
Eteplirsen 50mg/mL; per vial; soln for IV infusion after dilution; preservative-free.

Company:
Sarepta Therapeutics

Therapeutic Use:

Indications for EXONDYS 51:

Duchenne muscular dystrophy (DMD) in patients with a confirmed DMD gene mutation that is amenable to exon 51 skipping.

Adults and Children:

May apply topical anesthetic cream to IV site prior to administration. Give by IV infusion over 35–60mins. 30mg/kg once weekly.

Warnings/Precautions:

Renal or hepatic impairment. Pregnancy. Nursing mothers.

Interactions:

Do not mix or infuse with other medications concomitantly via same IV access line.

Pharmacological Class:

Antisense oligonucleotide.

Adverse Reactions:

Balance disorder, vomiting, contact dermatitis.

Generic Availability:

NO

How Supplied:

Single-dose vial (2mL, 10mL)—1

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