Depressive Disorders

Early Menarche Linked to Antisocial Behavior, Depression That Persists Into Adulthood

Early Menarche Linked to Antisocial Behavior, Depression That Persists Into Adulthood

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These results indicated a persistence of depressive and antisocial symptoms and related behavioral patterns far beyond what has been demonstrated in prior research.

Quality of Life May Be Improved in Chronic Pain With Multidisciplinary Social Cognitive Intervention

Quality of Life May Be Improved in Chronic Pain With Multidisciplinary Social Cognitive Intervention

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Social cognitive intervention may lead to improvements in health-related QoL in patients with chronic pain.

Treatment Initiation for Depression Suboptimal in Primary Care

Treatment Initiation for Depression Suboptimal in Primary Care

Treatment initiation for depression is suboptimal in the primary care setting despite availability.

Cranial electrical stimulation may be of modest benefit for treating depression and anxiety

Low-strength evidence suggests that cranial electrical stimulation (CES) may be moderately beneficial for patients with depression and anxiety. There was insufficient evidence that CES provides clinically important benefit for fibromyalgia, neuromusculoskeletal pain, degenerative joint pain, headache, depression, or insomnia.

Antidepressants More Effective Than Placebo for Acute Depression in Adults

Antidepressants More Effective Than Placebo for Acute Depression in Adults

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By bringing together published and unpublished data from more than 500 double-blind, randomized, controlled trials, this study represents the best currently available evidence base to guide the choice of pharmacologic treatment for adults with acute depression.

Effects of Depression, Alcohol Use on Retention in Antiretroviral Therapy

Effects of Depression, Alcohol Use on Retention in Antiretroviral Therapy

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Alcohol use disorder and depression were both associated with higher disengagement from antiretroviral therapy for patients with HIV.

Third Trimester Maternal SSRI Exposure Linked to Depression, Anxiety in Offspring

Third Trimester Maternal SSRI Exposure Linked to Depression, Anxiety in Offspring

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The issue of whether and how prenatal SSRI exposure affects offspring has remained murky.

Dermatologists May Need Further Training in Identifying Depression

Dermatologists May Need Further Training in Identifying Depression

Fair to poor concordance was seen between dermatologist assessment and patient self-reporting.

Examining Anxious Depression: Differences in Course and Outcomes

Examining Anxious Depression: Differences in Course and Outcomes

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Variability in definitions of "anxious depression" in research impedes the ability to make clear comparisons.

Neuroinflammation Associated With Anxiety, Depression in Multiple Sclerosis

Neuroinflammation Associated With Anxiety, Depression in Multiple Sclerosis

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In patients with multiple sclerosis, neuroinflammation is linked to anxiety and depression.

Psychosocial Intervention Improves Early Adherence to Antidepressants

Psychosocial Intervention Improves Early Adherence to Antidepressants

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Early adherence is an especially problematic, significant and modifiable barrier to quality care for depression.

Risk of Anxiety Disorder Relapse After Discontinuing Antidepressants

Risk of Anxiety Disorder Relapse After Discontinuing Antidepressants

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Researchers examined whether the risk of relapse or time to relapse was related to type of anxiety disorder, duration of previous treatment, and other factors.

Examining Rates of Conversion From Unipolar Depression to Bipolar Disorder

Examining Rates of Conversion From Unipolar Depression to Bipolar Disorder

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Making mental health predictions based on clinical presentation has major limitations.

Augmentation Therapy for Treatment-Resistant Major Depressive Disorder

Augmentation Therapy for Treatment-Resistant Major Depressive Disorder

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Augmentation therapy for treatment-resistant major depressive disorder includes multiple options with different strengths and limitations.

Anxiety and Depression's Effect on BMD in Anorexia

Anxiety and Depression's Effect on BMD in Anorexia

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Scores for both anxiety and depression are associated with low BMD.

Depression, Anxiety May Affect Bone Metabolism in Young Adults

Depression, Anxiety May Affect Bone Metabolism in Young Adults

In young adults, MDD, GAD, and SSRI use is associated with bone metabolism.

Depression Treatment May Benefit from Use of Ketamine

Depression Treatment May Benefit from Use of Ketamine

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Ketamine can provide acute benefits for treatment-resistant depression, bipolar depression, and major depressive disorder with suicidal ideation.

Bipolar Disorder Symptoms Lessened by Cognitive-Behavioral Therapy

Bipolar Disorder Symptoms Lessened by Cognitive-Behavioral Therapy

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CBT is effective in patients with bipolar disorder in decreasing the relapse rate and improving symptoms of depression and mania severity.

Antidepressant Side Effects More Common with Comorbid Panic Disorder

Antidepressant Side Effects More Common with Comorbid Panic Disorder

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Therapeutic response to antidepressants is highly variable, which may be partially due to associated side effects.

Assessing Internet-Based Depression Prevention in Chronic Back Pain

Assessing Internet-Based Depression Prevention in Chronic Back Pain

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Methods to prevent depression could help reduce the disease burden for both affected persons and society.

Increased Risk of PTSD in Parents of Kids With Critical Heart Defects

Increased Risk of PTSD in Parents of Kids With Critical Heart Defects

The researchers proposed integrating mental health screening and treatment into pediatric cardiology care.

Rapid Increase in Opioid Dose Increases Risk of New-Onset Depression

Rapid Increase in Opioid Dose Increases Risk of New-Onset Depression

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Dose escalation may be a proxy for loss of control or undetected abuse known to be associated with depression.

Depression Often Untreated in Dialysis Patients

Depression Often Untreated in Dialysis Patients

Many dialysis patients also do not wish to receive aggressive treatment for their depression.

Which Antidepressants May Cause Birth Defects?

Which Antidepressants May Cause Birth Defects?

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Anything that has the potential to disturb the serotonin signaling process has the potential to result in a wide variety of malformations.

Worse Psychological Outcomes for Women Denied Abortion

Worse Psychological Outcomes for Women Denied Abortion

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There is no evidence that protecting women's mental health concerns should restrict abortion access.

Modifiable Psychological Factors Influence TKA for OA

Modifiable Psychological Factors Influence TKA for OA

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Psychological factors drive expectations of poor outcomes following total knee arthroplasty.

Aging a Stronger Predictor of Depression, Negative Mood Than Menopause

Aging a Stronger Predictor of Depression, Negative Mood Than Menopause

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Women in the menopausal transition and early postmenopause are at higher risk for depressive symptoms and negative mood than those in late postmenopause.

Depression Medication Linked to Increased Risk of ICH

Depression Medication Linked to Increased Risk of ICH

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Concomitant use of oral anticoagulants among people taking SSRIs contributed to a significantly higher risk for ICH.

Youth Depression Onset Predicted by Anxiety, Family History, Adversity

Youth Depression Onset Predicted by Anxiety, Family History, Adversity

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Fear and anxiety showed the strongest correlation with development of major depression in children.

Link Found Between Tension Headaches and Anxiety, Depression

Link Found Between Tension Headaches and Anxiety, Depression

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Patients with tension-type headaches had a significantly higher prevalence of anxiety and depression.

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