Depressive Disorders

Appetitive Symptoms, Fluoxetine, and Light Therapy: Predicting Treatment Response for Nonseasonal Major Depression

Appetitive Symptoms, Fluoxetine, and Light Therapy: Predicting Treatment Response for Nonseasonal Major Depression

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Researchers examined whether more severe appetitive symptoms predicted a positive response to light therapy.

Short Form of Geriatric Depression Scale May Be Useful Assessment Tool Across Adult Lifespan

Short Form of Geriatric Depression Scale May Be Useful Assessment Tool Across Adult Lifespan

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The GDS-15 uses short sentences and a yes/no format, which is easier for patients who are struggling with depression, fatigue, or cognitive impairment to tolerate.

Mind-Body Therapy and Psychiatry: Ancient Tools for Modern Practice

Mind-Body Therapy and Psychiatry: Ancient Tools for Modern Practice

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Meditation techniques have an ever-growing evidence base to support their use and have become increasingly accepted in Western medicine as helpful adjuncts to other therapies.

Parental Depression Associated With Increased Healthcare Utilization in Children, Adolescents

Parental Depression Associated With Increased Healthcare Utilization in Children, Adolescents

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A combination of factors may have been responsible for the association between parental depression and increased healthcare visits in their children, including shared genetic risks.

Depression Associated With More Severe Disease Activity, Functional Impairment in axSpA

Depression Associated With More Severe Disease Activity, Functional Impairment in axSpA

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Depression is common in patients with axSpA and is associated with more severe disease activity and functional impairment.

Antidepressants and Bleeding Risk: What's the Link?

Antidepressants and Bleeding Risk: What's the Link?

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Results showed an increased risk of bleeding with SRIs by 1.16-2.36 times with an even higher 3.17- to 10.9-fold risk with concomitant NSAIDs.

Marijuana Use Associated With Poorer Depression Outcomes, Increased Suicidal Ideation

Marijuana Use Associated With Poorer Depression Outcomes, Increased Suicidal Ideation

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These data suggest that marijuana use, particularly non-medical use, is associated with poorer depression and anxiety outcomes in psychiatric patients.

Brain Region Connectivities Mediate the Association Between Depression and Sleep Quality

Brain Region Connectivities Mediate the Association Between Depression and Sleep Quality

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These data suggest a neurologic basis for the relationship between sleep quality and depressive symptoms, even among patients with no clinical diagnosis of depression.

Escitalopram Treatment After Acute Coronary Syndrome May Improve Long-term Outcomes

Escitalopram Treatment After Acute Coronary Syndrome May Improve Long-term Outcomes

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Depression is associated with poorer outcomes in ACS and these findings suggest that this course of treatment may improve long-term major adverse cardiac event outcomes.

Parent-Child Interactive Intervention Cuts Depression

Parent-Child Interactive Intervention Cuts Depression

An intervention targeting depression in very young children can be effective in community settings.

Certain Neuroinflammatory Biomarkers Associated With Depressive Symptoms

Certain Neuroinflammatory Biomarkers Associated With Depressive Symptoms

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These data substantiate claims that certain neuroinflammatory biomarkers may predict depression symptoms or severity and could be useful in developing diagnostic and treatment strategies.

High-Frequency, Repetitive TMS May Reduce Suicidal Ideation in Adolescents With Depression

High-Frequency, Repetitive TMS May Reduce Suicidal Ideation in Adolescents With Depression

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Researchers believe this therapy shows potential as a brain-based approach for correcting cortical physiologic deficits in this population.

Food Addiction Phenotype in Obesity Associated With Higher Risk for Mood, Anxiety Disorders

Food Addiction Phenotype in Obesity Associated With Higher Risk for Mood, Anxiety Disorders

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The researchers noted that these findings highlight the complexity of obesity as a disease that shares a common etiology with some psychiatric and addictive disorders.

Antenatal Depression Associated With Altered Behavior in Offspring

Antenatal Depression Associated With Altered Behavior in Offspring

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The results showed that women with antenatal MDD have abnormal stress-related inflammation and cortisol levels, a shorter gestational length, neonates with suboptimal neurobehavioral function, and their 1-year-old infants have increased cortisol reactivity to stress.

Affective Instability Is an Important Predictor of Major Depressive Disorder

Affective Instability Is an Important Predictor of Major Depressive Disorder

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Findings revealed that women's self-reported affective instability predicted depressive symptoms over time.

Pregnant Women Today May Be at Higher Risk for Prenatal Depression Than Their Mothers' Generation

Pregnant Women Today May Be at Higher Risk for Prenatal Depression Than Their Mothers' Generation

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Prenatal depression may be more common today among young pregnant women than among women in their mothers' generation.

Depression, Apathy Associated With Increased Risk for Mild Cognitive Impairment

Depression, Apathy Associated With Increased Risk for Mild Cognitive Impairment

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Adults with depressive symptoms and apathy in middle and late life were at a higher risk for conversion to mild cognitive impairment (MCI) and dementia.

FDA Fast-Tracks Novel Treatment for Major Depressive Disorder

FDA Fast-Tracks Novel Treatment for Major Depressive Disorder

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An investigational treatment for major depressive disorder, AGN-241751, has been granted Fast Track designation by the FDA.

FDA Approval of Medication With a Digital Monitoring System: Major Breakthrough or "Brave New World"?

FDA Approval of Medication With a Digital Monitoring System: Major Breakthrough or "Brave New World"?

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Abilify MyCite adds a digital sensor to the medication aripiprazole. The sensor, an ingestible event marker, is activated by contact with stomach acids and transmits a signal to a skin patch the patient wears, which then transmits to an app.

Problem Solving Helps Prevent Depression in Low-Income Moms

Problem Solving Helps Prevent Depression in Low-Income Moms

Problem-solving education is effective at preventing depressive symptoms among low-income mothers.

Omega-3 Fatty Acids Offer No Therapeutic Advantage Over Placebo for Adolescent Depression

Omega-3 Fatty Acids Offer No Therapeutic Advantage Over Placebo for Adolescent Depression

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These results challenge existing conceptions that omega-3 fatty acids may be effective in treating adolescent major depressive disorder.

Early Treatment for Depression in Bereaved Youth Improves Future Psychiatric Health

Early Treatment for Depression in Bereaved Youth Improves Future Psychiatric Health

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Bereaved children were more likely to experience depression, and children who lost a parent before the age of 12 were more likely to experience depression within the first 2 years.

Prenatal antidepressant exposure may increase risk of poor motor development

A meta-analysis of 18 studies examining the association of prenatal antidepressant exposure with motor development in children showed a small overall effect of worse motor development outcomes among children exposed to antidepressants in pregnancy.

Exposure to Antidepressants in Utero May Affect Childhood Motor Development

Exposure to Antidepressants in Utero May Affect Childhood Motor Development

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While the findings do not warrant a change in current prescribing practices, researchers advocate monitoring at-risk children in light of the increased use of antidepressants during pregnancy.

Lipophilic Statins Not Associated With Significant Increase in Risk for Depression

Lipophilic Statins Not Associated With Significant Increase in Risk for Depression

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Research has suggested a number of possible relationships with lipophilic statins, including a protective phenomenon against depression and higher risk for dementia, although these associations remain controversial.Research has suggested a number of possible relationships with lipophilic statins, including a protective phenomenon against depression and higher risk for dementia, although these associations remain controversial.

Fatigue a Potential Indicator of Overlapping Sleep Apnea and COPD

Fatigue a Potential Indicator of Overlapping Sleep Apnea and COPD

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On the basis of these findings, researchers recommended that "[f]atigue should be evaluated whenever there is clinical suspicion of overlap syndrome."

Novel Parent-Child Interaction Therapy Targets Preschool-Aged Depression

Novel Parent-Child Interaction Therapy Targets Preschool-Aged Depression

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Children in the waiting list group exhibited significantly worse impairments on the Preschool Feelings Checklist at the study's end, but children who completed the therapy showed improvements in emotion regulation and guilt processing.

Midlife Fitness Associated With Lower Risk for Depression and CVD Death

Midlife Fitness Associated With Lower Risk for Depression and CVD Death

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These results demonstrate the importance of midlife fitness to prevent depression and subsequent CVD mortality in older age.

Depression, Anxiety May Correlate With Disease Activity in Early Rheumatoid Arthritis

Depression, Anxiety May Correlate With Disease Activity in Early Rheumatoid Arthritis

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This research provides further support to compelling data linking inflammation and depression.

Remission of Treatment-Resistant Depression in Veterans Depends on Close Clinical Observation

Remission of Treatment-Resistant Depression in Veterans Depends on Close Clinical Observation

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This study supports the effects of close clinical observation and the use of combined treatment interventions including repetitive transcranial magnetic stimulation for achieving remission in veterans with treatment-resistant depression.

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