Depressive Disorders

Augmentation Therapy for Treatment-Resistant Major Depressive Disorder

Augmentation Therapy for Treatment-Resistant Major Depressive Disorder

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Augmentation therapy for treatment-resistant major depressive disorder includes multiple options with different strengths and limitations.

Anxiety and Depression's Effect on BMD in Anorexia

Anxiety and Depression's Effect on BMD in Anorexia

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Scores for both anxiety and depression are associated with low BMD.

Depression, Anxiety May Affect Bone Metabolism in Young Adults

Depression, Anxiety May Affect Bone Metabolism in Young Adults

In young adults, MDD, GAD, and SSRI use is associated with bone metabolism.

Depression Treatment May Benefit from Use of Ketamine

Depression Treatment May Benefit from Use of Ketamine

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Ketamine can provide acute benefits for treatment-resistant depression, bipolar depression, and major depressive disorder with suicidal ideation.

Bipolar Disorder Symptoms Lessened by Cognitive-Behavioral Therapy

Bipolar Disorder Symptoms Lessened by Cognitive-Behavioral Therapy

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CBT is effective in patients with bipolar disorder in decreasing the relapse rate and improving symptoms of depression and mania severity.

Antidepressant Side Effects More Common with Comorbid Panic Disorder

Antidepressant Side Effects More Common with Comorbid Panic Disorder

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Therapeutic response to antidepressants is highly variable, which may be partially due to associated side effects.

Assessing Internet-Based Depression Prevention in Chronic Back Pain

Assessing Internet-Based Depression Prevention in Chronic Back Pain

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Methods to prevent depression could help reduce the disease burden for both affected persons and society.

Increased Risk of PTSD in Parents of Kids With Critical Heart Defects

Increased Risk of PTSD in Parents of Kids With Critical Heart Defects

The researchers proposed integrating mental health screening and treatment into pediatric cardiology care.

Rapid Increase in Opioid Dose Increases Risk of New-Onset Depression

Rapid Increase in Opioid Dose Increases Risk of New-Onset Depression

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Dose escalation may be a proxy for loss of control or undetected abuse known to be associated with depression.

Depression Often Untreated in Dialysis Patients

Depression Often Untreated in Dialysis Patients

Many dialysis patients also do not wish to receive aggressive treatment for their depression.

Which Antidepressants May Cause Birth Defects?

Which Antidepressants May Cause Birth Defects?

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Anything that has the potential to disturb the serotonin signaling process has the potential to result in a wide variety of malformations.

Worse Psychological Outcomes for Women Denied Abortion

Worse Psychological Outcomes for Women Denied Abortion

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There is no evidence that protecting women's mental health concerns should restrict abortion access.

Modifiable Psychological Factors Influence TKA for OA

Modifiable Psychological Factors Influence TKA for OA

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Psychological factors drive expectations of poor outcomes following total knee arthroplasty.

Aging a Stronger Predictor of Depression, Negative Mood Than Menopause

Aging a Stronger Predictor of Depression, Negative Mood Than Menopause

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Women in the menopausal transition and early postmenopause are at higher risk for depressive symptoms and negative mood than those in late postmenopause.

Depression Medication Linked to Increased Risk of ICH

Depression Medication Linked to Increased Risk of ICH

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Concomitant use of oral anticoagulants among people taking SSRIs contributed to a significantly higher risk for ICH.

Youth Depression Onset Predicted by Anxiety, Family History, Adversity

Youth Depression Onset Predicted by Anxiety, Family History, Adversity

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Fear and anxiety showed the strongest correlation with development of major depression in children.

Link Found Between Tension Headaches and Anxiety, Depression

Link Found Between Tension Headaches and Anxiety, Depression

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Patients with tension-type headaches had a significantly higher prevalence of anxiety and depression.

Cytokine Levels May Predict SSRI Response in Children and Adolescents

Cytokine Levels May Predict SSRI Response in Children and Adolescents

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Elevated cytokine levels could help to identify children who are unlikely to respond to treatment with fluoxetine.

Executive Dysfunction in Idiopathic Depression vs Epilepsy-associated Depression

Executive Dysfunction in Idiopathic Depression vs Epilepsy-associated Depression

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Individuals suffering from depression, as well as persons diagnosed with temporal lobe epilepsy, present with dysfunction across several cognitive domains.

Cigarette Smoking Predicts Development of Depression

Cigarette Smoking Predicts Development of Depression

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Cigarette smoking prevalence among persons with severe mental illness is approximately 3 times greater than the rate observed in the general population.

Depressive Symptoms Linked to Shorter Survival With Lung Cancer

Depressive Symptoms Linked to Shorter Survival With Lung Cancer

Depression symptoms at baseline correlated with increased mortality among participants with early- but not late-stage disease.

Sertraline Prevents Depression Following Traumatic Brain Injury

Sertraline Prevents Depression Following Traumatic Brain Injury

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Approximately 80% of depressive episodes have their onset during the first six months following traumatic brain injury.

Pupillometric Analysis For Assessment of Depression Recurrence

Pupillometric Analysis For Assessment of Depression Recurrence

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Pupillary reactivity to emotional stimuli has been investigated to provide objective information about the risk for recurrence of depressive symptoms in women.

Mood Disorders and the Disrupted Gut Microbial Milieu

Mood Disorders and the Disrupted Gut Microbial Milieu

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Lower diversity of microbial populations in the human gut has been identified in individuals with major depressive disorder.

Comprehensive Assessment Essential for Treating All Aspects of Pain

Comprehensive Assessment Essential for Treating All Aspects of Pain

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Regular evaluation and assessment along with a personalized "step approach" is essential for effective pain management.

Internet Addiction May Signal Other Mental Health Issues

Internet Addiction May Signal Other Mental Health Issues

An over-reliance on the internet could indicate depression, anxiety, or impulsivity in college students.

Cognition in Depression: A Critical Domain for Health Outcomes, Measurement, and Treatment

Cognition in Depression: A Critical Domain for Health Outcomes, Measurement, and Treatment

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Dr. Roger McIntyre suggests that the clinical relevance of cognitive dysfunction for any individual patient can only be adjudicated on a case-by-case basis.

Whole Body Hyperthermia: The Future of Depression Treatment?

Whole Body Hyperthermia: The Future of Depression Treatment?

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Researchers investigated the lasting effects of whole body hyperthermia (WBH) in the first randomized, double-blind, [placebo]-controlled study of WBH for the treatment of MDD.

Does Impaired Cognition Precede Depression?

Does Impaired Cognition Precede Depression?

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Dysfunction across several cognitive domains is often concomitant with depression.

"Frequent Flyers" in Emergency Department More Likely to Have Depression

"Frequent Flyers" in Emergency Department More Likely to Have Depression

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"Detecting depression in the emergency department is of utmost importance," Dr. Brickman and colleagues wrote in their publication.

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