Depressive Disorder

Off-Label Antidepressant Use Not Supported By Strong Evidence

Off-Label Antidepressant Use Not Supported By Strong Evidence

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Prescribing antidepressants for off-label indications in primary care is often not supported by strong evidence for the respective indication.

Depressive Symptoms Linked to Minor Adverse Cardiovascular Events

Depressive Symptoms Linked to Minor Adverse Cardiovascular Events

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Depressive symptoms are associated with increased incidence of adverse cardiovascular events.

Bright Light Therapy for Nonseasonal Depression: An Emerging Intervention

Bright Light Therapy for Nonseasonal Depression: An Emerging Intervention

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Bright light therapy is an accepted treatment for seasonal affective disorder.

Mental Health Deficiencies Stem From Early Childhood Neglect

Mental Health Deficiencies Stem From Early Childhood Neglect

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A study of Romanian adoptees demonstrates that early childhood mistreatment can have a lasting psychological effect into adulthood.

Dementia, Depression Common Following ICH

Dementia, Depression Common Following ICH

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Among ICH survivors, 63% developed both depression and dementia during a 5-year follow-up study.

Antidepressant Death Found Most Often With Amitriptyline

Antidepressant Death Found Most Often With Amitriptyline

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Clinicians need to be aware of the potential risks when they prescribe antidepressants and other drugs used in the treatment of depression.

Depressive Symptoms Reduced in Older Adults

Depressive Symptoms Reduced in Older Adults

For older adults with subthreshold depression, collaborative care is associated with a reduction in depressive symptoms compared with usual care.

Poststroke Depression Risk in Women

Poststroke Depression Risk in Women

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Moderate optimism may be protective against the risk of new-onset depression in women who have a stroke.

Partner Practice After Meditation Alleviates Loneliness

Partner Practice After Meditation Alleviates Loneliness

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Clinicians should be mindful of interventions bolstering connectedness.

Treating Pain in Depression May Improve Cognitive, Functional Outcomes

Treating Pain in Depression May Improve Cognitive, Functional Outcomes

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Patients with pain and depression are more likely to have cognitive impairment.

Preschoolers With Depression Show Reduced Response to Rewards

Preschoolers With Depression Show Reduced Response to Rewards

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Altered reward sensitivity may be an indicator of depression in preschool-aged children.

Anxiety, Hopelessness With Huntington's Risk Most Predictive of Suicidal Ideation

Anxiety, Hopelessness With Huntington's Risk Most Predictive of Suicidal Ideation

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Behavioral symptoms strongly linked to suicidal ideation included depression, irritability, aggression, and impulsivity.

Depression, Poor Sleep Affects Hemodialysis Patients

Depression, Poor Sleep Affects Hemodialysis Patients

Those with depression had significantly more disturbed sleep quality, more daytime sleepiness, and had more problems sleeping due to restless leg syndrome.

Pilots Suffer Depression, Suicidal Thoughts at Fairly High Rates

Pilots Suffer Depression, Suicidal Thoughts at Fairly High Rates

Hundreds of active pilots manage depressive symptoms without the possibility of treatment due to fear of negative career impact.

Switching Antidepressants During Nonresponse May Be Ineffective

Switching Antidepressants During Nonresponse May Be Ineffective

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There is no conclusive benefit to switching to a new antidepressant during nonresponse.

Depressive Symptoms in AMD, Diabetic Retinopathy Reduced

Depressive Symptoms in AMD, Diabetic Retinopathy Reduced

Self-care tools can reduce depressive symptoms in patients with age-related macular degeneration (AMD) or diabetic retinopathy (DR).

16% of US Adults Report Psychiatric Drug Use

16% of US Adults Report Psychiatric Drug Use

1 in 6 US adults take a psychiatric medication to treat conditions such as depression, anxiety, and insomnia.

Clinical Antecedents of New Adolescent-Onset MDD Identified

Clinical Antecedents of New Adolescent-Onset MDD Identified

A new study identifies developmental pathways that lead to first-episode adolescent-onset MDD among offspring of depressed parents.

Medical Students at High Risk for Depression, Suicidal Ideation

Medical Students at High Risk for Depression, Suicidal Ideation

High levels of stress and responsibility lead to greater prevalence of depression and suicidal ideation in medical students.

Social Support a Significant Factor in Developing Anxiety, Depression in Epilepsy

Social Support a Significant Factor in Developing Anxiety, Depression in Epilepsy

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The number of AEDs and seizure frequency also influenced depression in people with epilepsy.

Electroconvulsive Therapy Continues to Be Vital Treatment for Depression in Elderly

Electroconvulsive Therapy Continues to Be Vital Treatment for Depression in Elderly

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Research findings support continuation of ECT plus medication in a depressed elderly population.

Psilocybin May Provide Swift Relief From Depression, Anxiety in Cancer Patients

Psilocybin May Provide Swift Relief From Depression, Anxiety in Cancer Patients

Researchers found that the hallucinogenic drug relieves depression and anxiety quickly, and that the effect can last for months.

Migraine Intensity Affects Muscle Pain in Major Depressive Disorder

Migraine Intensity Affects Muscle Pain in Major Depressive Disorder

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Migraine was more significantly associated with muscle soreness or pain than anxiety disorders in patients with MDD.

Transcranial Magnetic Stimulation Provides Pain Relief Independent of Improvements in Depression

Transcranial Magnetic Stimulation Provides Pain Relief Independent of Improvements in Depression

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Repetitive transcranial magnetic stimulation of the right secondary somatosensory motor cortex produces relief from chronic neuropathic orofacial pain.

Short-Term Suicide Risk For Discharged Psychiatric Hospital Patients

Short-Term Suicide Risk For Discharged Psychiatric Hospital Patients

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Because much of the previous research in this subject area has focused on the suicide risk of one disorder, little is known about risk of suicide across multiple disorders or in general medical conditions with psychiatric comorbidities.

The ADA Issues Guidelines for Psychosocial Care in Diabetes

The ADA Issues Guidelines for Psychosocial Care in Diabetes

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The ADA released detailed guidelines for psychosocial assessments and care based on factors including age, type of diabetes, and family support system.

Maternal Pre- and Postpartum Depression Affects Child's Brain Development

Maternal Pre- and Postpartum Depression Affects Child's Brain Development

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A significant gender effect was observed in the cohort, but the mechanism behind it remains unclear.

ACR: Mind-Body Training Improves Depression in SLE

ACR: Mind-Body Training Improves Depression in SLE

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No studies to date have evaluated psychotherapy approaches in people with lupus and comorbid depression.

Depression Rates Up Among Adolescents, Particularly Females

Depression Rates Up Among Adolescents, Particularly Females

The report authors propose cyberbullying and social media use as possible theories, but at this point these remain speculative.

Risk of Serotonin Toxicity Due to Drug-Drug Interactions in Migraine Treatment

Risk of Serotonin Toxicity Due to Drug-Drug Interactions in Migraine Treatment

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Clinicians need to remain vigilant when prescribing tramadol; its concurrent use with opioids poses a risk of serotonin toxicity.

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