Depressive Disorder News Archive
Treatment initiation for depression is suboptimal in the primary care setting despite availability.
By bringing together published and unpublished data from more than 500 double-blind, randomized, controlled trials, this study represents the best currently available evidence base to guide the choice of pharmacologic treatment for adults with acute depression.
Alcohol use disorder and depression were both associated with higher disengagement from antiretroviral therapy for patients with HIV.
The issue of whether and how prenatal SSRI exposure affects offspring has remained murky.
Fair to poor concordance was seen between dermatologist assessment and patient self-reporting.
In patients with multiple sclerosis, neuroinflammation is linked to anxiety and depression.
Early adherence is an especially problematic, significant and modifiable barrier to quality care for depression.
Researchers examined whether the risk of relapse or time to relapse was related to type of anxiety disorder, duration of previous treatment, and other factors.
Augmentation therapy for treatment-resistant major depressive disorder includes multiple options with different strengths and limitations.
Scores for both anxiety and depression are associated with low BMD.
In young adults, MDD, GAD, and SSRI use is associated with bone metabolism.
Ketamine can provide acute benefits for treatment-resistant depression, bipolar depression, and major depressive disorder with suicidal ideation.
CBT is effective in patients with bipolar disorder in decreasing the relapse rate and improving symptoms of depression and mania severity.
Therapeutic response to antidepressants is highly variable, which may be partially due to associated side effects.
Methods to prevent depression could help reduce the disease burden for both affected persons and society.
The researchers proposed integrating mental health screening and treatment into pediatric cardiology care.
Dose escalation may be a proxy for loss of control or undetected abuse known to be associated with depression.
Many dialysis patients also do not wish to receive aggressive treatment for their depression.
Anything that has the potential to disturb the serotonin signaling process has the potential to result in a wide variety of malformations.
There is no evidence that protecting women's mental health concerns should restrict abortion access.
Psychological factors drive expectations of poor outcomes following total knee arthroplasty.
Women in the menopausal transition and early postmenopause are at higher risk for depressive symptoms and negative mood than those in late postmenopause.
Concomitant use of oral anticoagulants among people taking SSRIs contributed to a significantly higher risk for ICH.
Fear and anxiety showed the strongest correlation with development of major depression in children.
Patients with tension-type headaches had a significantly higher prevalence of anxiety and depression.
Elevated cytokine levels could help to identify children who are unlikely to respond to treatment with fluoxetine.
Individuals suffering from depression, as well as persons diagnosed with temporal lobe epilepsy, present with dysfunction across several cognitive domains.
Cigarette smoking prevalence among persons with severe mental illness is approximately 3 times greater than the rate observed in the general population.
Depression symptoms at baseline correlated with increased mortality among participants with early- but not late-stage disease.
Approximately 80% of depressive episodes have their onset during the first six months following traumatic brain injury.
Pupillary reactivity to emotional stimuli has been investigated to provide objective information about the risk for recurrence of depressive symptoms in women.
Lower diversity of microbial populations in the human gut has been identified in individuals with major depressive disorder.
Regular evaluation and assessment along with a personalized "step approach" is essential for effective pain management.
An over-reliance on the internet could indicate depression, anxiety, or impulsivity in college students.
Researchers investigated the lasting effects of whole body hyperthermia (WBH) in the first randomized, double-blind, [placebo]-controlled study of WBH for the treatment of MDD.
Dysfunction across several cognitive domains is often concomitant with depression.
"Detecting depression in the emergency department is of utmost importance," Dr. Brickman and colleagues wrote in their publication.
The registry contains more than 10,000 EEGs and 38,000 pharmacological outcomes, and is accessible to clinicians worldwide.
Brain-derived Neurotrophic Factor and its Precursor proBDNF as Diagnostic Biomarkers for Mood Disorders
mBDNF/proBDNF ratio could potentially serve as a novel biomarker for mood disorders.
Atrophy of numerous structures within the central nervous system has been observed in persons suffering from depression.
Dementia risk was particularly elevated in patients with depression who had higher scores on cognitive tests at baseline.
The First Baby Study at Penn State College of Medicine includes more than 3 000 women in Pennsylvania having their first baby.
Irritability in Recovered Bipolar Disorder Patients Linked to Greater Morbidity, Depression Recurrence
Delayed depressive recovery occurred more in depressed patients with current irritability.
Understanding distinct patterns of comorbid substance use may be more relevant to prevention and treatment than focusing on one individual substance.
Individuals diagnosed with melancholic major depressive disorder presented with more severe symptoms of depression compared with persons with non-melancholic depression.
Sustained anterior cingulate cortex activation during rewarding events predicted better treatment response to Behavioral Activation Treatment for Depression.
Risk highest among patients with psych symptoms pre-ICU/psych distress symptoms while in ICU
Psychosocial and Demographic Predictors of Depression Among Individuals With Bipolar Disorder and Schizophrenia
Bipolar disorder and schizophrenia are characterized by significant genetic overlap, as well as significant clinical presentation overlap.
Grandchildren with both a depressed parent and depressed grandparent were at highest risk for MDD.
An analysis of the SF-36 health survey found that the survey can accurately determine the presence of psychological disorders in patients with RA, and suggests that a threshold of ≤38 on the mental component summary score may be optimal to screen for these disorders.
Inflated DAS28 may indicate significant psychological morbidity and related non-inflammatory pain, rather than true rheumatoid arthritis disease activity.
Childhood is a critical developmental period in the brain's response to traumatic stress such as family adversity.
In terms of depressive and negative symptoms, in the present meta-analysis, researchers estimate that 1 in 9 patients with schizophrenia will improve with add-on antidepressants.
The accuracy of the PHQ-2 in identifying major depression is lower than originally thought.
Bipolar disorder (BD) is typically characterized by recurrent episodes of mania and depression, but the connection between BD and anxiety needs to be considered.
The findings could have important clinical implications in the treatment of patients with arthritis.
Adolescents who experience chronic pain have higher prevalence of anxiety and depressive symptoms in adulthood.
Events that happen in childhood and adolescence can predispose individuals to suicidal behavior.
Augmentation and combination approaches with pharmaceuticals are often used in clinical practice.
Interventions are needed to enhance adherence to prescribed medications, especially in older adults experiencing new episodes of depression.
Identifying environmental factors that put teens at risk for suicidal behavior is crucial.
Peripheral Inflammatory Markers Are Associated With Psychomotor Retardation in Major Depressive Disorder
Psychomotor retardation is associated with poor response to antidepressant treatment.
Socioeconomic status was the only environmental stressor that predicted an increase in SLC6A4 proximal promoter methylation.
Major depressive disorder is a highly disabling condition that affects nearly 15 million American adults in a given year.
The most common off-label uses were for insomnia (10.2%) and pain (6.1%).
Polymorphisms of the GRIK4 gene modulate the response to electroconvulsive therapy.
This small-scale feasibility study did not include a control group.
Aversive conditioned stimulus-elicited habenula response decreased in individuals diagnosed with major depression.
Manipulating gene networks across distinct brain regions in mice affects susceptibility or resilience to depression-like behavior.
Age-dependent structural brain abnormalities identified in adolescents and adults with major depressive disorder.
Those in the calorie cutting group said their sleep and relationships also improved.
Clinicians should focus on treating patients' pain and psychological conditions together.
Having more information on the long-term impact of antidepressants on weight could reduce the risk of weight-related morbidity for a large population of adults with depression.
Depression is one of many factors that can predict an inadequate treatment response in patients with episodic migraine.
How does a high carbohydrate or low carbohydrate weight loss diet affect depression in type 2 diabetes?
The risk of cardiovascular disease as a person's depression improves or worsens has largely remained unknown.
Research has found that patients with AS have an increased risk of developing certain depressive disorders following their diagnosis.
Neither a specific antidepressant class nor individual drugs had any influence on the risk of stroke or transient ischemic attack over all of follow-up.
Although researchers are not certain about the mechanisms driving the link between depression and coffee or caffeine consumption, several potential explanations have emerged.
Treatment gives infusions of ketamine no more than once per week.
Modestly obese women who were educated were almost twice as likely to have depression than their normal-weight peers.
Significantly less use of care management processes for depression compared with asthma, congestive heart failure, or diabetes.
Paroxetine use improved cognitive impairment and reduced inflammation in HIV patients.
Study suggests statins may play a role in the development of new-onset depression.
Study is the first to compare suicide risk of new mothers with postpartum disorder to other categories of women.
The Attempted Suicide Short Intervention Program is a low-cost psychiatric intervention for patients in a hospital after an attempt.
Students with self-described addictive behaviors toward smartphones or the Internet scored higher on anxiety and depression scales.
Mice repeatedly exposed to an aggressive intruder had a difficult time remembering locations in a previously mastered maze.
Only 44% of pediatricians ask mothers during child visits about maternal depression.
Transgender children who have socially transitioned have only minimal elevations in anxiety.
Decline in QOL and increase in depressive symptoms during hospitalization predict six-month outcomes.
Attention bias modification is intended to shift one's attention away from negative stimuli.
The research represents the first general population study of assortative mating in psychiatric disorders.
The number and timing of follow-up psychotherapy visits may be inadequate to deliver evidence-based psychotherapy.
Insufficient evidence to recommend screening for children aged 11 and younger.
Reductions in sweat-related health problems, anxiety and depression, symptom severity.
Smoking pot, however, is significantly associated with any substance use, alcohol use, drug use disorders.
Results from a new survey suggest that significant gaps exist in the treatment for adults in the US with major depressive disorder.
Preemies may possess elevated levels of characteristics that put them at risk for peer victimization, including more anxiety and depression.
New research suggests that a group of drugs being developed for mood disorders could also relieve chronic pain.
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Psychiatry Advisor Articles
- Adjunctive Therapies for Bipolar Disorder Show Promise, Need More Evidence
- Improving Performance of Everyday Activities Is Critical in Schizophrenia
- Analysis Finds Lithium Maintenance Most Effective as Monotherapy in Bipolar Disorder
- Web-Based Intervention Targets Parental Behaviors That May Affect Adolescent Anxiety, Depression
- Abnormalities of Cortical Thickness in Bipolar Disorder With Auditory Hallucinations
- The Way to the Head May Be Through the Gut: Probiotics for Depression
- Suicide-Screening Toolkit Can Help Identify Youths at High Risk for Suicide
- Agoraphobia: An Evolving Understanding of Definitions and Treatment
- Parental Pressure to Diet Linked With Long-term Harm in Adolescents
- Does Access to Medical Cannabis Reduce Risk for Opioid Abuse?
- Antidepressants Increase Seizure Risk in Youth and Severely Depressed
- Examining Associations Between Diabetes and Effects on Cognition
- Untreated Depression Common in Women of Childbearing Age
- Incidence of Psychiatric Disorders in Rheumatoid Arthritis
- Effect of Antidepressant Class, Dose on Pediatric Anxiety Disorders