Depressive Disorder News Archive
These results demonstrate the importance of midlife fitness to prevent depression and subsequent CVD mortality in older age.
This research provides further support to compelling data linking inflammation and depression.
This study supports the effects of close clinical observation and the use of combined treatment interventions including repetitive transcranial magnetic stimulation for achieving remission in veterans with treatment-resistant depression.
Investigators note that depression should be evaluated and treated in patients with multiple sclerosis and may hinder balance rehabilitation.
Patients with these cardiovascular diseases would benefit from early psychiatric help.
These data may be useful to clinicians in gaining insight on the potential risks of cannabis use among their patients with anxiety or mood disorders.
Technology-Enhanced Intervention in the ED Appears Promising for Reducing Underage Drinking, Consequences
This intervention provides flexibility in the clinical setting, allowing for therapist delivery when staff is available and computer delivery when staff resources are not available.
Clinicians may find these data useful in treating patients with major depressive disorder and an inadequate response to antidepressant treatment alone.
It may be important to increase awareness of avoiding negative social media encounters to reduce the risk for depressive symptoms.
The researchers believe this study is the first to detect a statistically significant, unexpected inverse association between efavirenz use and depression.
The age association remained significant after additional adjustments for clinical and social factors such as loneliness and pain. As such, age-specific factors cannot alone explain the poorer MDD course associated with older age.
Investigators sought to determine the frequency of major depressive disorder in patients in epilepsy clinics.
Carefully assessing cognitive performance using a screening test to detect visuospatial/executive, attention, and memory dysfunction in patients with migraine.
An estimated 37.2% of people in the United States use medications that have an adverse effect of depression.
Preliminary generalizations point toward the potential therapeutic efficacy of targeting loneliness and social support for patients.
The notion that abortion harms women's mental health may be misinformed and should be re-examined according to scientific data such as these.
This study was prompted by an ongoing shortage of injectable caffeine sodium benzoate in the United States from 2011 to 2017.
These analyses may serve clinicians in addressing potential psychiatric obstacles in patients undergoing fertility treatments.
These data may be helpful in developing targeted interventions for women at risk for postpartum depression.
As this and previous research on dose increase strategies have produced inconsistent findings, the researchers recommended clinicians consider other responses to antidepressant treatment failure, at least for selective serotonin reuptake inhibitors.
These data could be useful to clinicians and patients alike in selecting the proper treatment method.
The Janssen Pharmaceutical Companies of Johnson & Johnson have announced the results of 2 long-term phase 3 clinical trials examining esketamine nasal spray in patients with treatment-resistant depression.
Among men, those with active major depression were less likely to have a partner achieve conception.
Examining the Relationship Between Childhood Anxiety, Depression and Risk for Cardiovascular Disease
The potential plasticity of the cardiovascular system during childhood may explain the lack of significant relationship between depression and anxiety symptomatology and CVD risk in this study population.
Routine assessments of these markers should be conducted before and during treatment as they may inform prognoses.
The relationship between pain and cognitive dysfunction was explained by sleep disturbance and depressive symptoms.
Carbamazepine, in particular, was associated with lower hazards for depression and anxiety in secondary analyses.
Active major depression in the male partner may lower the likelihood of pregnancy.
The erythematotelangiectatic, papulopustular, phymatous, and ocular forms of rosacea can lead to psychological distress.
A substantial proportion of these individuals diagnosed with HIV, psychiatric disorders, and substance use disorders are out of care and urgently require intervention.
These findings suggest a strong association between greater depressive symptoms and markers of brain aging as well as impaired episodic memory.
Widespread use of antidepressants may be contributing to long-term increased risk for weight gain.
When assessing risk for postpartum episodes, clinicians should inquire about family history of psychiatric disorders broadly and not limit discussion to postpartum psychiatric disorders or psychiatric disorders in female relatives.
Baseline depressive symptoms were associated with pain and disability in adolescents with juvenile idiopathic arthritis.
Sedentary behavior is closely linked to a more articulated pattern of psychological variables, largely influenced by sex-related differences in the individual psychological characteristics.
Gender may not influence vulnerability for developing new-onset depression during interferon-alpha therapy.
A placebo-controlled study could further clarify these results and possibly strengthen the case for antidepressant treatment for depression in vascular cognitive impairment.
Despite the widespread use of antidepressants for treating insomnia, the evidence for their effectiveness remains limited.
Diagnoses of major depression have increased since 2013, particularly among adolescents and millennials.
This study had a sample size large enough to assess the effect of circadian disruption on mental health disorders, and was the first to objectively measure patterns of rest and activity (using accelerometers).
Mental health problems are 1 of the most important reasons for failing to engage in long-term control of HIV.
Multimarker inflammatory biosignatures are expected to facilitate diagnosis and predict treatment outcomes for various central nervous system disorders, particularly Alzheimer disease and major depressive disorder.
Investigators assessed whether depressive symptoms during and after pregnancy were associated with neurodevelopmental disadvantages in children.
Clinicians should take depression into careful consideration when treating patients with Alzheimer dementia, as the two conditions combined may predispose patients to cardiovascular disease more than either condition alone.
The average MADRS-10 scores decreased from baseline, and this decrease was maintained at the end of the study.
Lundbeck announced that the Food and Drug Administration has approved a supplemental New Drug Application for Trintellix.
These findings suggest an urgent need for improved measures of social and clinical support in transgender and/or gender-nonconforming youth.
Findings highlight the clinical importance of enhanced treatment protocols designed to reduce the duration and frequency of depressive episodes in women living with HIV.
Although there were no indications of esketamine dependence, misuse, diversion, or withdrawal symptoms in this trial, this is a possible concern, and the authors call for further evidence from clinical trials to evaluate the drug's potential for abuse.
For individuals with major depression and bipolar disorder, grip strength is positively associated with cognition.
Results in the 202B and 202C trials showed that brexanolone achieved the primary endpoint of mean reduction from baseline in the Hamilton Rating Scale for Depression.
Communities that favor consanguineous marriage should receive sensitive advice on the risks involved to aid in reproductive decision making.
Patients with MS and comorbid psychiatric conditions have increased severity of subsequent neurological disability.
These data indicate a potential association between prenatal SSRI exposure and the development of the fetal amygdala-insula circuit, possibly via anomalous serotonin signaling.
The prevalence of depression and anxiety are increased among survivors of colorectal cancer.
Mothers struggling with depression may benefit from additional breastfeeding education and support.
Major depressive disorder with psychotic features had comparative long-term outcomes with schizophrenia, schizoaffective disorder, and bipolar disorder.
Recognizing the increased risk for mood disorders in children with ASD and ADHD may be useful for clinicians and parents in developing proper screening and treatment strategies.
Children of first-cousin consanguineous parents have increased odds of mental health issues and needing antidepressant medications.
Selective serotonin reuptake inhibitors and other antidepressants, such as tricyclic antidepressants, are associated with increased adverse outcomes in patients aged 20 to 64 years diagnosed with depression.
Ceasing regular exercise increases depressive symptoms, particularly in women.
Individuals with chronic pain and comorbid depression may experience higher levels of stigma related to their conditions compared with patients with chronic pain alone.
Many non-pregnant women of childbearing age are suffering from untreated depression.
The incidence and prevalence of psychiatric disorders such as depression, anxiety, and bipolar disorder are higher in the rheumatoid arthritis population.
Practice guidelines have been updated to assist primary care physicians in the screening and treatment of adolescent depression.
These results indicated a persistence of depressive and antisocial symptoms and related behavioral patterns far beyond what has been demonstrated in prior research.
Quality of Life May Be Improved in Chronic Pain With Multidisciplinary Social Cognitive Intervention
Social cognitive intervention may lead to improvements in health-related QoL in patients with chronic pain.
Treatment initiation for depression is suboptimal in the primary care setting despite availability.
By bringing together published and unpublished data from more than 500 double-blind, randomized, controlled trials, this study represents the best currently available evidence base to guide the choice of pharmacologic treatment for adults with acute depression.
Alcohol use disorder and depression were both associated with higher disengagement from antiretroviral therapy for patients with HIV.
The issue of whether and how prenatal SSRI exposure affects offspring has remained murky.
Fair to poor concordance was seen between dermatologist assessment and patient self-reporting.
In patients with multiple sclerosis, neuroinflammation is linked to anxiety and depression.
Early adherence is an especially problematic, significant and modifiable barrier to quality care for depression.
Researchers examined whether the risk of relapse or time to relapse was related to type of anxiety disorder, duration of previous treatment, and other factors.
Augmentation therapy for treatment-resistant major depressive disorder includes multiple options with different strengths and limitations.
Scores for both anxiety and depression are associated with low BMD.
In young adults, MDD, GAD, and SSRI use is associated with bone metabolism.
Ketamine can provide acute benefits for treatment-resistant depression, bipolar depression, and major depressive disorder with suicidal ideation.
CBT is effective in patients with bipolar disorder in decreasing the relapse rate and improving symptoms of depression and mania severity.
Therapeutic response to antidepressants is highly variable, which may be partially due to associated side effects.
Methods to prevent depression could help reduce the disease burden for both affected persons and society.
The researchers proposed integrating mental health screening and treatment into pediatric cardiology care.
Dose escalation may be a proxy for loss of control or undetected abuse known to be associated with depression.
Many dialysis patients also do not wish to receive aggressive treatment for their depression.
Anything that has the potential to disturb the serotonin signaling process has the potential to result in a wide variety of malformations.
There is no evidence that protecting women's mental health concerns should restrict abortion access.
Psychological factors drive expectations of poor outcomes following total knee arthroplasty.
Women in the menopausal transition and early postmenopause are at higher risk for depressive symptoms and negative mood than those in late postmenopause.
Concomitant use of oral anticoagulants among people taking SSRIs contributed to a significantly higher risk for ICH.
Fear and anxiety showed the strongest correlation with development of major depression in children.
Patients with tension-type headaches had a significantly higher prevalence of anxiety and depression.
Elevated cytokine levels could help to identify children who are unlikely to respond to treatment with fluoxetine.
Individuals suffering from depression, as well as persons diagnosed with temporal lobe epilepsy, present with dysfunction across several cognitive domains.
Cigarette smoking prevalence among persons with severe mental illness is approximately 3 times greater than the rate observed in the general population.
Depression symptoms at baseline correlated with increased mortality among participants with early- but not late-stage disease.
Approximately 80% of depressive episodes have their onset during the first six months following traumatic brain injury.
Pupillary reactivity to emotional stimuli has been investigated to provide objective information about the risk for recurrence of depressive symptoms in women.
Lower diversity of microbial populations in the human gut has been identified in individuals with major depressive disorder.
Regular evaluation and assessment along with a personalized "step approach" is essential for effective pain management.
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Psychiatry Advisor Articles
- FOSTA-SESTA Threatens Sex Worker Livelihoods: What Mental Health Providers Should Know
- Psychotic Experiences Associated With Increased Risk for Eating Disorders in Adolescents
- Younger Gestational Age Associated With Symptoms of ADHD in Children
- Strong Social Networks May Mitigate the Effects of Childhood Adversity
- Suicidal Behavior More Likely in Depression, Bipolar Disorder With Mixed Features
- Medical Clearance of Psych Patients in the ED: Consensus Recommendations
- From Abused Child to Serial Killer: Investigating Nature vs Nurture in Methods of Murder
- Managing Comorbid Migraine and Mood Disorders: A Synergistic Approach
- Dialectical Behavior Therapy Effective in Reducing Suicide Attempts, Self-Harm in Adolescents
- Novel Parent-Child Interaction Therapy Targets Preschool-Aged Depression
- Early Treatment for Depression in Bereaved Youth Improves Future Psychiatric Health
- Posttraumatic Stress Disorder Symptoms Reduced With Virtual Reality Therapy
- Wellness Vacations Bring a Healthy Lifestyle to the Forefront of Travel
- The Harmful Application of HIPAA: How to Protect Privacy and Patient Care
- Gender Bias in Medicine Has Far-Reaching Consequences