dementia

Drug Therapy Guidance Lacking for Sleep Disorders in Dementia

Drug Therapy Guidance Lacking for Sleep Disorders in Dementia

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A Cochrane systematic review found a clear lack of evidence for pharmacologic guidance of sleep problems in dementia.

Exploring Possible Causes of Decreasing Dementia Rates In the US

Exploring Possible Causes of Decreasing Dementia Rates In the US

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Better management of cardiovascular risk factors and higher levels of education may have contributed to this improvement.

MRI May Help Identify Lewy Body Dementia vs Alzheimer's

MRI May Help Identify Lewy Body Dementia vs Alzheimer's

Someone whose hippocampus stayed the same size was nearly 6 times more likely to develop Lewy body dementia.

Loneliness May Be a Precursor to Alzheimer's Disease

Loneliness May Be a Precursor to Alzheimer's Disease

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Recognition of self-reported symptoms that may appear at early onset of amyloid accumulation, such as loneliness, point to opportunities for preventive therapies.

Too Few Seniors Planning End-of-Life Care

Too Few Seniors Planning End-of-Life Care

Findings suggest that efforts to encourage more planning aren't working.

Probability of Dementia Higher in Men Receiving Androgen Deprivation Therapy

Probability of Dementia Higher in Men Receiving Androgen Deprivation Therapy

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The longer the duration of ADT, the greater the risk of dementia.

High Thyroid Hormone Levels May Increase Dementia Risk

High Thyroid Hormone Levels May Increase Dementia Risk

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One hypothesis is that thyroid function affects dementia risk through nonvascular pathways.

Sundowning: Phenomenology, Pathophysiology, and Treatment Approaches

Sundowning: Phenomenology, Pathophysiology, and Treatment Approaches

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Sundowning is a complex multifactorial condition that has eluded rigorous understanding of its pathophysiological causes.

Symptoms of Re-experiencing the Traumatic Event Predict Cognitive Impairment

Symptoms of Re-experiencing the Traumatic Event Predict Cognitive Impairment

New study highlights the importance of re-experiencing symptoms, a major component of PTSD, in predicting cognitive impairment.

Late-onset Depression Associated with Elevated Dementia Risk

Late-onset Depression Associated with Elevated Dementia Risk

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Dementia risk was particularly elevated in patients with depression who had higher scores on cognitive tests at baseline.

Deep Brain Stimulation Appears Safe in Alzheimer's

Deep Brain Stimulation Appears Safe in Alzheimer's

Participants aged ≥65 years may have derived benefit from stimulation, while there was possible worsening in patients below age 65 years.

Vascular Intervention Appears Not To Affect Dementia Incidence

Vascular Intervention Appears Not To Affect Dementia Incidence

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Cases of all-cause dementia and Alzheimer's did not significantly differ between study groups, but vascular care is safe and may reduce incidence of non-Alzheimer's dementia.

No Evidence for Transmission of Alzheimer Pathology Through Blood Transfusions

No Evidence for Transmission of Alzheimer Pathology Through Blood Transfusions

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If transmission of neurodegenerative diseases such as dementia of any type, AD, or PD does occur, it is rare.

Cannabinoids Reduce Intraneuronal Beta Amyloid Protein Levels

Cannabinoids Reduce Intraneuronal Beta Amyloid Protein Levels

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Tetrahydrocannabinol (THC) is the main active chemical ingredient found in cannabis and is a potent cannabinoid receptor (CB)-1 agonist.

Physical Activity During Midlife Influences Late Life Verbal Memory Performance

Physical Activity During Midlife Influences Late Life Verbal Memory Performance

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Modifiable risk factors (eg, smoking, hypertension, sedentary behavior, overweight/obesity, and social engagement) contribute to nearly half of documented dementia cases.

Could Alzheimer's Disease be Caused by Infections?

Could Alzheimer's Disease be Caused by Infections?

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Although inconclusive, late-onset Alzheimer's Disease could be triggered by infectious pathogens.

Prevalence of Pseudobulbar Affect in Patients With Dementia

Prevalence of Pseudobulbar Affect in Patients With Dementia

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Symptoms of PBA were observed in nearly three-quarters of patients with dementia.

Atrial Fibrillation, Warfarin Use May Increase Dementia Risk

Atrial Fibrillation, Warfarin Use May Increase Dementia Risk

Patients with atrial fibrillation who have been treated with warfarin may have an increased risk of developing dementia.

Increasing Depressive Symptoms Associated with Dementia Risk

Increasing Depressive Symptoms Associated with Dementia Risk

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The trajectory of increasing depressive symptoms was associated with a higher risk of dementia.

Novel Case: Alzheimer's Reported in HIV+ Patient

Novel Case: Alzheimer's Reported in HIV+ Patient

The case suggests that some patients with HIV and dementia may be misdiagnosed with HIV-associated brain disorders.

Improved Cognitive Assessment Test to Screen for Dementia

Improved Cognitive Assessment Test to Screen for Dementia

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Administration time for cognitive assessment screenings is currently suboptimal in many clinical settings.

Sensory Stimulation May Benefit Patients with Dementia

Sensory Stimulation May Benefit Patients with Dementia

Researchers identified 8 categories of sensory stimulation interventions that significantly influenced dementia.

Colonic Diverticular Disease May Increase Dementia Risk

Colonic Diverticular Disease May Increase Dementia Risk

Researchers found an elevated risk of dementia after adjustment for age, sex, and comorbidities.

Physical Activity Level Affects Rate of Cognitive Decline

Physical Activity Level Affects Rate of Cognitive Decline

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Declines in processing sleep and episodic memory were observed in those with low levels of activity.

Dementia Risk Greater When Depression Symptoms Increase Over Time

Dementia Risk Greater When Depression Symptoms Increase Over Time

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Whether depression is a risk factor for dementia or a symptom of an underlying neurodegenerative process is a complex question.

Incidence of Dementia Decreased in Framingham Heart Study

Incidence of Dementia Decreased in Framingham Heart Study

Researchers found a decrease in dementia incidence over 3 decades for participants under surveillance since 1975.

Algorithm Aims to Predict Dementia Risk with Routine Data

Algorithm Aims to Predict Dementia Risk with Routine Data

The algorithm is potentially useful for patients aged 60 to 79 years, but not for people older than 80. More research is needed before it can be used.

Moderate Drinking May Reduce Mortality in Early-Stage Alzheimer's

Moderate Drinking May Reduce Mortality in Early-Stage Alzheimer's

Those who had 2 to 3 alcoholic drinks a day had a 77% lower risk of dying during the study period than those who had 1 or fewer drinks a day.

Vascular Conditions, Stroke May Contribute to Alzheimer's Disease

Vascular Conditions, Stroke May Contribute to Alzheimer's Disease

More research on the link between vascular conditions, Alzheimer's disease, and dementia can help identify new treatments and preventions.

Caregivers of Those With Dementia Carry Significant Burden

Caregivers of Those With Dementia Carry Significant Burden

Levels of "burden" continued to rise among caregivers through as their care continued.

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