Generic Name and Formulations:
Cyproheptadine HCl 4mg; scored tabs.
Various generic manufacturers
Indications for Cyproheptadine:
Allergic and vasomotor rhinitis, conjunctivitis, urticaria, angioedema, reactions to blood. Adjunct in anaphylaxis. Cold urticaria. Dermatographism.
≥14yrs: initially 4mg 3 times daily; usual range 12–16mg/day; max 0.5mg/kg per day.
<2yrs: not recommended. 2–6yrs: 2mg 2–3 times per day; max 12mg daily. 7–14yrs: 4mg 2–3 times per day; max 16mg daily.
MAOIs. Glaucoma. GI or urinary obstruction. Elderly. Debilitated. Neonates. Premature infants. Nursing mothers.
Hyperthyroidism. Cardiovascular disease. Hypertension. Increased intraocular pressure. History of asthma. Pregnancy (Cat.B).
See Contraindications. Anticholinergic effects potentiated by MAOIs. Potentiates CNS depression with alcohol, other CNS depressants.
Drowsiness, dizziness, paradoxical excitement, anticholinergic effects, gastritis, hypotension, blood dyscrasias.
Formerly known under the brand name Periactin.
Sign Up for Free e-newsletters
Psychiatry Advisor Articles
- Family History of Psychiatric Disorders an Important Predictor of Postpartum Psychiatric Illness
- Antidepressant Use May Be Linked With Sustained Risk for Weight Gain
- MDMA-Assisted Psychotherapy Effective for Treating PTSD in Veterans, First Responders
- New APA President Takes Office as the First African-American to Lead the Organization
- Substance Abuse and Primary Psychosis: A Closer Look
- Electroconvulsive Therapy Effective in Children With Autism
- The Cutting Edge of Schizophrenia Research: VR as Treatment for Psychosis
- Cannabidiol Not Associated With Improvement in Chronic Schizophrenia
- Methadone Maintenance Therapy Associated With Greater Access to Physician Care in HCV-Positive Drug Users
- Mental Health Comorbidity Examined in Transgender and Gender-Nonconforming Youth
- New Dimensions in Psychopathy: Are There Cultural Differences in Psychopaths?
- Addressing Psychiatric Comorbidities in Inflammatory Rheumatic Diseases
- Exploring the Link Between Persistent Infection, Inflammation, and Mood Disorders
- CDC: No Change in Level of Uninsured in US in 2017
- Benefit of Behavioral Activation During TMS for Major Depressive Disorder