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CONRAY 30
Imaging agents
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Drug Name:

CONRAY 30 Rx

Generic Name and Formulations:
Iothalamate meglumine 300mg/mL; soln for IV infusion; organically bound iodine 141mg/mL.

Company:
Mallinckrodt, Inc.

Therapeutic Use:

Indications for CONRAY 30:

For use in IV infusion urography, contrast enhancement of computed tomographic brain images and arterial digital subtraction angiography.

Adult:

IV urography: Infuse at a rate of 50mL/min. 200–300mL (4mL/kg); max 300mL. Non-neoplastic conditions: 200–300mL. Arterial digital subtraction angiography: Carotid or vertebral arteries: 3–10mL; Aortic arch: 15–30mL; Subclavian and brachial arteries: 5–15mL; Major branches of the aorta: 5–30mL; Abdominal aorta: 10–30mL. Max total dose: 250mL.

Children:

Non-neoplastic conditions: <100lbs: 4mL/kg.

Contraindications:

Myelography. Others: see full labeling.

Warnings/Precautions:

Not for intrathecal use. Should be administered by professional trained in use of radiopaque agents in appropriate facilities with emergency treatment readily available. Avoid in homocystinuria. Subarachnoid hemorrhage. Multiple myeloma. Pheochromocytoma. Homozygous sickle cell disease. Primary or metastatic cerebral lesions; risk of convulsions. Advanced renal disease. Combined renal and hepatic disease. Severe hypertension. CHF. Recent renal transplant. Diabetes. Diabetic nephropathy. Hyperthyroidism. Endotoxemia. Elevated body temperatures. History of asthma/allergy. Elderly. Maintain adequate hydration. Pregnancy (Cat.B - Conray 30, 60; Cat.C - Conray 43). Nursing mothers: not recommended; avoid breastfeeding for 24hrs post-procedure.

See Also:

CONRAY 43

CONRAY 60

Pharmacological Class:

Radiopaque contrast medium.

Adverse Reactions:

GI upset, facial flushing, body warmth; hypersensitivity reactions, cardiovascular reactions (eg, vasodilation, flushing, venospasm), inj site reactions, neurological reactions (eg, spasm, convulsions, aphasia, syncope, coma, death), endocrine reactions (eg, hypothyroidism), headache, shaking, chills, nephropathy.

How Supplied:

Conray 30: Bottles (150mL)—12; Conray 43: Vials (50mL)—50; Bottles (250mL)—12; Conray 60: Vials (30mL, 50mL)—50; Bottles (100mL, 150mL)—12

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