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Cefaclor Extended-Release Tablets
Bacterial infections
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Drug Name:

Cefaclor Extended-Release Tablets Rx

Generic Name and Formulations:
Cefaclor 375mg, 500mg; ext-rel tabs.

Company:
Various generic manufacturers

Therapeutic Use:

Indications for Cefaclor Extended-Release Tablets:

Susceptible mild to moderate infections including acute exacerbations of chronic bronchitis, secondary infections of acute bronchitis, pharyngitis/tonsillitis, uncomplicated skin and skin structures.

Adult:

Take with meals. Swallow whole. Cefaclor ext-rel tab 500mg twice daily clinically equivalent to caps 250mg three times daily. ≥16yrs: Bronchitis: 500mg every 12 hrs for 7 days. Pharyngitis/tonsillitis: 375mg every 12 hrs for 10 days. Skin and skin structures: 375mg every 12 hrs for 7–10 days.

Children:

<16yrs: not recommended.

Warnings/Precautions:

Penicillin or other allergy. Discontinue if colitis occurs and treat. Severe renal dysfunction. GI disease (esp. colitis). Pregnancy (Cat.B). Nursing mothers.

Interactions:

May cause false (+) Coomb's test or glucose test with Clinitest or Benedict's or Fehling's soln. Potentiated by probenecid. Monitor warfarin. ER: antagonized by concomitant (within 1 hr) aluminum or magnesium-containing antacids.

See Also:

Cefaclor Capsules

Cefaclor Suspension

Pharmacological Class:

Cephalosporin.

Adverse Reactions:

Headache, GI upset, rash, blood dyscrasias, hepatic dysfunction, cough, CNS stimulation, serum-sickness-like reactions.

Note:

Formerly known under the brand names Ceclor CD (ext-rel tabs); Ceclor (caps, susp); Raniclor (caps).

How Supplied:

Contact supplier.

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