Cannabis-Use Disorder

Crystal Structure of Cannabinoid Receptor 1 Determined: Implications for Managing Pain

Crystal Structure of Cannabinoid Receptor 1 Determined: Implications for Managing Pain

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The crystal structure may provide inspiration for designing drugs that refine efficacy and avoid adverse events.

Reduced Bone Density Among Heavy Users of Cannabis

Reduced Bone Density Among Heavy Users of Cannabis

Researchers find heavy users have lower bone density than cigarette smokers.

THC Causes Cognitive Indolence in Rats

THC Causes Cognitive Indolence in Rats

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Δ9-Tetrahydrocannabinol (THC) is the main psychoactive chemical ingredient in cannabis.

Marijuana May Damage Heart More Than Tobacco

Marijuana May Damage Heart More Than Tobacco

One minute of exposure impaired endothelial function in rats for at least 90 minutes.

Marijuana Poisonings in Toddlers Rising in Colorado

Marijuana Poisonings in Toddlers Rising in Colorado

Marijuana-laced candy and baked goods are attractive to children, increasing calls to poison centers.

Synthetic Cannabinoid Drug Poisonings Surge

Synthetic Cannabinoid Drug Poisonings Surge

The increased use of synthetic cannabinoids presents a serious public health threat.

Long-term Marijuana Use Associated with Dampened Nucleus Accumbens Reward Response

Long-term Marijuana Use Associated with Dampened Nucleus Accumbens Reward Response

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Alterations in reward processing may increase users' risk of continued drug use and subsequent addiction.

Severe Cannabis Dependence and Blunted Striatal Dopamine Release: A Comorbidity Independent Effect

Severe Cannabis Dependence and Blunted Striatal Dopamine Release: A Comorbidity Independent Effect

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Chronic and severe cannabis-dependence is associated with deficits in striatal dopamine release.

Marijuana Hair Testing: An Accurate Method for Detecting Consumption?

Marijuana Hair Testing: An Accurate Method for Detecting Consumption?

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Marijuana use is associated with development of various neuropsychiatric conditions such as schizophrenia, anxiety, and depression.

Declining Marijuana Use, Conduct Problems Among Adolescents

Declining Marijuana Use, Conduct Problems Among Adolescents

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Cannabis use disorder (CUD) is currently the most widely reported illegal substance use disorder.

Link Between Genetic Variation, Lifetime Cannabis Use Found

Link Between Genetic Variation, Lifetime Cannabis Use Found

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Approximately 30% of users exhibit signs of marijuana abuse or dependence.

Cannabis Use Has a Negative Impact on Gum Health

Cannabis Use Has a Negative Impact on Gum Health

Prolonged cannabis use is a risk factor for periodontal disease.

Synthetic Cannabinoids: A Public Health Concern

Synthetic Cannabinoids: A Public Health Concern

The increased use of synthetic cannabinoids presents a public health threat.

Marijuana Use in Male Teenagers Linked to Earlier Mortality

Marijuana Use in Male Teenagers Linked to Earlier Mortality

Study links heavy cannabis use in male teens to increased mortality by age 60.

Genes Associated With Cannabis Dependence Identified

Genes Associated With Cannabis Dependence Identified

Genome-wide association identified 3 independent regions with single nucleotide polymorphisms.

The Benefits and Consequences of Legalized Marijuana

The Benefits and Consequences of Legalized Marijuana

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Questions remain as to whether botanically-derived marijuana offers clinical benefit over pharmaceutical-grade THC, its active ingredient.

Increased ED Visits in Colorado Tied to Cannabis

Increased ED Visits in Colorado Tied to Cannabis

Visits to the emergency department for out-of-state individuals increased following legalization of cannabis in Colorado.

Genetic Variant Could Identify Cannabis Users at Risk for Psychosis

Genetic Variant Could Identify Cannabis Users at Risk for Psychosis

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Healthy participants with a variation in the AKT1 gene were at higher risk of acute psychotic response to cannabis.

Using Marijuana Doesn't Boost Anxiety, Mood Disorders Risk

Using Marijuana Doesn't Boost Anxiety, Mood Disorders Risk

Smoking pot, however, is significantly associated with any substance use, alcohol use, drug use disorders.

Past Marijuana Use Could Worsen Verbal Memory In Mid-Life

Past Marijuana Use Could Worsen Verbal Memory In Mid-Life

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Users whose cumulative marijuana use exceeded the equivalent of one joint a day for five years had a significant decline in verbal memory in middle age.

Tanning Increases Substance Abuse in Teens

Tanning Increases Substance Abuse in Teens

Found more likely to smoke, drink, and use illegal drugs and steroids.

Cannabis Produces Transient Psychosis-Like Effects

Cannabis Produces Transient Psychosis-Like Effects

If the link between neural noise and psychosis is confirmed, it could help researchers have a better understanding of schizophrenia symptoms.

Concentrated Cannabis Can Damage Brain's White Matter

Concentrated Cannabis Can Damage Brain's White Matter

Frequent use of high-potency marijuana was associated with a higher level of white matter damage.

Ten Percent of Adults Have a Drug-Use Disorder in Their Lifetime

Ten Percent of Adults Have a Drug-Use Disorder in Their Lifetime

About 4% of Americans are currently battling a substance-use disorder.

Genetics May Influence Marijuana Dependence in Childhood Abuse Victims

Genetics May Influence Marijuana Dependence in Childhood Abuse Victims

A certain variation in a gene was associated with cannabis dependence in child abuse victims.

Marijuana Use and Abuse Rising

Marijuana Use and Abuse Rising

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The most notable increases in marijuana use were in women, blacks, Hispanics, people living in the South, and those middle-aged or older.

No Evidence To Support Cannabis/Schizophrenia Link

No Evidence To Support Cannabis/Schizophrenia Link

Brain researcher says no studies have ever demonstrated that there is a risk of long-term psychosis with marijuana use.

Abuse of Psychoactive Drugs Most Common Among Men, Whites

Abuse of Psychoactive Drugs Most Common Among Men, Whites

Participants who had used substances such as synthetic marijuana or bath salts were also more likely to have used illicit drugs.

Adolescents With Chronic Illnesses Susceptible to Marijuana, Alcohol

Adolescents With Chronic Illnesses Susceptible to Marijuana, Alcohol

Twenty percent of high school students with conditions including cystic fibrosis and type 1 diabetes have smoked marijuana.

Marijuana Changes Brain, But Doesn't Shrink It

Marijuana Changes Brain, But Doesn't Shrink It

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The effects of cannabis, however, may be the most pronounced in those who are at the greatest risk for psychosis or addiction.

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