Cannabis-Use Disorder

Substance Use Disorders Associated With Conversion From Schizotypal Disorder to Schizophrenia

Substance Use Disorders Associated With Conversion From Schizotypal Disorder to Schizophrenia

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These data may be helpful in titrating care for those with schizotypal disorder and comorbid substance abuse disorders to mitigate the risk for conversion to schizophrenia.

Significant variation in mortality trends in substance use disorders among US counties

Mortality rates decreased for alcohol use disorders, self-harm, and interpersonal violence between 1980 and 2014. Mortality rates for drug use disorders increased both nationally and in each county over the same period.

Antisocial and Borderline Personality Disorders Associated With Cannabis Use

Antisocial and Borderline Personality Disorders Associated With Cannabis Use

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The investigators found that antisocial (β=0.23) and borderline (β=0.20) personality disorders were strongly associated with cannabis use as well as with cannabis use disorder.

Increased Odds of Cigarette Use, Relapse Among Cannabis Users

Increased Odds of Cigarette Use, Relapse Among Cannabis Users

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The findings of these analyses suggest that, to an extent, this relationship might be generalized to cannabis users as a whole, not just those diagnosed with a cannabis use disorder.

Scale of Online Marketplace for Marijuana Increasing

Scale of Online Marketplace for Marijuana Increasing

Online marijuana searches grew by 98 percent as a proportion of all searches from 2005 to 2017.

Mortality Rates for Substance Use Disorders, Intentional Injuries Vary Widely By County

Mortality Rates for Substance Use Disorders, Intentional Injuries Vary Widely By County

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Researchers calculated age-standardized mortality rates on a county level in the United States between 1980 and 2014, specifically examining rates for self-harm, interpersonal violence, alcohol use, and drug use.

Cannabis Use Associated With Subsequent Psychotic Experiences in Adolescents

Cannabis Use Associated With Subsequent Psychotic Experiences in Adolescents

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Both early-onset cannabis users and late-onset cannabis users had an increased risk for psychotic experiences at age 18.

Cannabis Use in Adolescence May Mediate Future Hypomania

Cannabis Use in Adolescence May Mediate Future Hypomania

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Frequent cannabis use was associated with subsequent hypomania.

Illicit Marijuana Use Increased in States With Legal Medical Use

Illicit Marijuana Use Increased in States With Legal Medical Use

Cannabis use disorder is also rising faster in states that have legalized marjiuana.

Crystal Structure of Cannabinoid Receptor 1 Determined: Implications for Managing Pain

Crystal Structure of Cannabinoid Receptor 1 Determined: Implications for Managing Pain

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The crystal structure may provide inspiration for designing drugs that refine efficacy and avoid adverse events.

Reduced Bone Density Among Heavy Users of Cannabis

Reduced Bone Density Among Heavy Users of Cannabis

Researchers find heavy users have lower bone density than cigarette smokers.

THC Causes Cognitive Indolence in Rats

THC Causes Cognitive Indolence in Rats

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Δ9-Tetrahydrocannabinol (THC) is the main psychoactive chemical ingredient in cannabis.

Marijuana May Damage Heart More Than Tobacco

Marijuana May Damage Heart More Than Tobacco

One minute of exposure impaired endothelial function in rats for at least 90 minutes.

Marijuana Poisonings in Toddlers Rising in Colorado

Marijuana Poisonings in Toddlers Rising in Colorado

Marijuana-laced candy and baked goods are attractive to children, increasing calls to poison centers.

Synthetic Cannabinoid Drug Poisonings Surge

Synthetic Cannabinoid Drug Poisonings Surge

The increased use of synthetic cannabinoids presents a serious public health threat.

Long-term Marijuana Use Associated with Dampened Nucleus Accumbens Reward Response

Long-term Marijuana Use Associated with Dampened Nucleus Accumbens Reward Response

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Alterations in reward processing may increase users' risk of continued drug use and subsequent addiction.

Severe Cannabis Dependence and Blunted Striatal Dopamine Release: A Comorbidity Independent Effect

Severe Cannabis Dependence and Blunted Striatal Dopamine Release: A Comorbidity Independent Effect

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Chronic and severe cannabis-dependence is associated with deficits in striatal dopamine release.

Marijuana Hair Testing: An Accurate Method for Detecting Consumption?

Marijuana Hair Testing: An Accurate Method for Detecting Consumption?

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Marijuana use is associated with development of various neuropsychiatric conditions such as schizophrenia, anxiety, and depression.

Declining Marijuana Use, Conduct Problems Among Adolescents

Declining Marijuana Use, Conduct Problems Among Adolescents

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Cannabis use disorder (CUD) is currently the most widely reported illegal substance use disorder.

Link Between Genetic Variation, Lifetime Cannabis Use Found

Link Between Genetic Variation, Lifetime Cannabis Use Found

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Approximately 30% of users exhibit signs of marijuana abuse or dependence.

Cannabis Use Has a Negative Impact on Gum Health

Cannabis Use Has a Negative Impact on Gum Health

Prolonged cannabis use is a risk factor for periodontal disease.

Synthetic Cannabinoids: A Public Health Concern

Synthetic Cannabinoids: A Public Health Concern

The increased use of synthetic cannabinoids presents a public health threat.

Marijuana Use in Male Teenagers Linked to Earlier Mortality

Marijuana Use in Male Teenagers Linked to Earlier Mortality

Study links heavy cannabis use in male teens to increased mortality by age 60.

Genes Associated With Cannabis Dependence Identified

Genes Associated With Cannabis Dependence Identified

Genome-wide association identified 3 independent regions with single nucleotide polymorphisms.

The Benefits and Consequences of Legalized Marijuana

The Benefits and Consequences of Legalized Marijuana

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Questions remain as to whether botanically-derived marijuana offers clinical benefit over pharmaceutical-grade THC, its active ingredient.

Increased ED Visits in Colorado Tied to Cannabis

Increased ED Visits in Colorado Tied to Cannabis

Visits to the emergency department for out-of-state individuals increased following legalization of cannabis in Colorado.

Genetic Variant Could Identify Cannabis Users at Risk for Psychosis

Genetic Variant Could Identify Cannabis Users at Risk for Psychosis

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Healthy participants with a variation in the AKT1 gene were at higher risk of acute psychotic response to cannabis.

Using Marijuana Doesn't Boost Anxiety, Mood Disorders Risk

Using Marijuana Doesn't Boost Anxiety, Mood Disorders Risk

Smoking pot, however, is significantly associated with any substance use, alcohol use, drug use disorders.

Past Marijuana Use Could Worsen Verbal Memory In Mid-Life

Past Marijuana Use Could Worsen Verbal Memory In Mid-Life

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Users whose cumulative marijuana use exceeded the equivalent of one joint a day for five years had a significant decline in verbal memory in middle age.

Tanning Increases Substance Abuse in Teens

Tanning Increases Substance Abuse in Teens

Found more likely to smoke, drink, and use illegal drugs and steroids.

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