CALCIUM DISODIUM VERSENATE Rx
Generic Name and Formulations:
Edetate calcium disodium (EDTA) 200mg/mL; IV, IM inj.
Bausch Health Companies Inc.
Indications for CALCIUM DISODIUM VERSENATE:
Lead poisoning. Lead encephalopathy.
Adults and Children:
See full labeling. Maintain hydration. IM for children and overt lead encephalopathy. Blood lead levels 20–70micrograms/dL: 1g/m2 per day. IV: infuse over 8–12 hours. IM: divided doses every 8–12 hours. Treat for 5 days then stop for 2–4 days; may repeat. If levels over 70micrograms/dL: give with BAL; see full labeling.
Anuria. Renal disease. Hepatitis.
Risk of potentially fatal toxic effects (see full labeling).
Increased intracranial pressure (IV). Monitor urinalysis, urinary sediment, electrolytes, renal and hepatic function. Discontinue at 1st sign of renal toxicity. Pregnancy (Cat.B). Nursing mothers.
Steroids may increase renal toxicity. May chelate zinc in insulin preparations.
Acute necrosis of proximal tubules (may result in fatal nephrosis), fever, chills, malaise, hypotension, arrhythmias, zinc deficiency, hypercalcemia, glycosuria, proteinuria, hematuria, large epithelial cells in urinary sediment, GI upset, polydipsia, histamine-like reactions, transient bone marrow depression, anemia, local reactions.
Sign Up for Free e-newsletters
Psychiatry Advisor Articles
- Nomophobia: The Modern-Day Pathology
- Emerging Theories in the Pathophysiology of MDD: Could the Opioid System Be Involved?
- Transdermal Nicotine Boosts Mood and Cognitive Function in Late-Life Depression
- Combination Cognitive Behavioral Therapy With Fluoxetine Effective for Adolescent Depression
- Prazosin May Be Effective as Treatment for Alcohol Use Disorder
- Text Message Reminders Improve Medication Adherence in Bipolar I Disorder
- Improving Medication Adherence in ADHD Lowers Risk for Oppositional Defiant Disorder, Conduct Disorder in Adulthood
- High Suicidality Among Children With ADHD Mediated by Family Functioning, Psychiatry Comorbidities
- Pilot Study Investigates Lithium vs Quetiapine for Bipolar Spectrum Disorder
- How Personalized Hospital Ratings May Drive Patient-Specific Care in the Digital Age