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Butalbital/Acetaminophen/Caffeine
Migraine and headache
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Drug Name:

Butalbital/Acetaminophen/Caffeine Rx

Generic Name and Formulations:
Butalbital 50mg, acetaminophen 325mg, caffeine 40mg; tabs; caps.

Company:
Various generic manufacturers

Therapeutic Use:

Indications for Butalbital/Acetaminophen/Caffeine:

Tension (or muscle contraction) headache.

Adult:

1–2 tabs or caps every 4hrs as needed; max 6 daily.

Children:

Not established.

Contraindications:

Porphyria.

Warnings/Precautions:

Drug abusers. Severe hepatic or renal impairment (monitor). Acute abdominal conditions. Discontinue if serious skin rash or hypersensitivity reactions occur. Elderly. Debilitated. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

May potentiate effects of alcohol, general anesthetics, tranquilizers, sedative-hypnotics, or other CNS depressants or narcotic analgesics; avoid. MAOIs may enhance CNS effects of butalbital. May cause false (+) urine test for 5-hydroxyindoleacetic acid.

Pharmacological Class:

Barbiturate + analgesic.

Adverse Reactions:

Drowsiness, lightheadedness, dizziness, sedation, shortness of breath, nausea, vomiting, abdominal pain, intoxicated feeling; hepatotoxicity (APAP doses >4g/day); rare: serious skin reactions, hypersensitivity.

Note:

Formerly known under the brand name Esgic.

How Supplied:

Contact supplier.

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