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BLEPHAMIDE
Ocular allergy/inflammation
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Drug Name:

BLEPHAMIDE Rx

Generic Name and Formulations:
Sulfacetamide sodium 10%, prednisolone acetate 0.2%; oph susp; contains benzalkonium chloride.

Company:
Allergan

Therapeutic Use:

Indications for BLEPHAMIDE:

Ocular inflammation with infection.

Adults and Children:

<6yrs: not established. ≥6yrs: 2 drops every 4 hours and at bedtime or small amount of ointment 3–4 times daily and 1–2 times at night. May prolong dosing interval as condition improves; max 20mL or 8g per therapeutic course. Re-evaluate if no improvement after 2 days.

Contraindications:

Ocular fungal, viral, or mycobacterial infections.

Warnings/Precautions:

Corneal or scleral thinning: increased risk of perforation. Glaucoma. Severe dry eye. Purulent exudates may inactivate sulfonamides. Cataract surgery: may delay healing and increase bleb formation. May mask signs of infection. Monitor for secondary ocular infections (eg, fungal) and intraocular pressure in prolonged use (≥10 days). Discontinue if rash or hypersensitivity reactions occur. Avoid abrupt cessation. Pregnancy. Nursing mothers: not recommended.

Interactions:

Incompatible with silver-containing preparations. Antagonized by PABA.

See Also:

BLEPHAMIDE S.O.P. OINT

Pharmacological Class:

Sulfonamide + steroid.

Adverse Reactions:

Ocular irritation, secondary ocular infections; rare: severe sulfonamide reactions (eg, Stevens-Johnson syndrome, toxic epidermal necrolysis, fulminant hepatic necrosis, blood dyscrasias). In prolonged use: increased IOP, cataracts, optic nerve damage.

How Supplied:

Susp—5mL, 10mL; Oint—3.5g

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