Bipolar Disorders

Medication Adherence Predictors in Patients With Severe Psychiatric Disorders

Medication Adherence Predictors in Patients With Severe Psychiatric Disorders

By

As antipsychotic medications are vital to the effective management of severe psychiatric disorders, investigators sought to examine reasons for medication nonadherence in patients with schizophrenia, bipolar disorders, and other psychotic disorders.

Abnormal Frontal Gyrus, Limbic Activity Observed During Attentional Activity in Pediatric Bipolar Disorder

Abnormal Frontal Gyrus, Limbic Activity Observed During Attentional Activity in Pediatric Bipolar Disorder

By

These results may be helpful in elucidating the specific brain mechanisms of bipolar disorder during cognitive development.

Personality Disorders Related to Adverse Outcomes in Bipolar Disorder

Personality Disorders Related to Adverse Outcomes in Bipolar Disorder

By

These data may lead to a more nuanced understanding of bipolar disorder and to a better definition of the effectiveness of interventions directed at treating both personality disorders and bipolar disorder.

Relationship Between Impulsivity, Sleep Changes in Adolescents With Bipolar Disorder

Relationship Between Impulsivity, Sleep Changes in Adolescents With Bipolar Disorder

By

Sleep routines may be an important therapeutic target for adolescents with bipolar disorder.

Examining Treatment Modalities for Noninvasive Brain Stimulation for Adult Depression

Examining Treatment Modalities for Noninvasive Brain Stimulation for Adult Depression

By

These data could be useful to clinicians and patients alike in selecting the proper treatment method.

HIV Viral Suppression Rates in Psychiatric Inpatients With Comorbid Substance Use Disorders

HIV Viral Suppression Rates in Psychiatric Inpatients With Comorbid Substance Use Disorders

By

A substantial proportion of these individuals diagnosed with HIV, psychiatric disorders, and substance use disorders are out of care and urgently require intervention.

Family History of Psychiatric Disorders an Important Predictor of Postpartum Psychiatric Illness

Family History of Psychiatric Disorders an Important Predictor of Postpartum Psychiatric Illness

By

When assessing risk for postpartum episodes, clinicians should inquire about family history of psychiatric disorders broadly and not limit discussion to postpartum psychiatric disorders or psychiatric disorders in female relatives.

Childhood-Onset Bipolar Disorder Associated With Impaired Family Functioning

Childhood-Onset Bipolar Disorder Associated With Impaired Family Functioning

By

Further investigation into the family-based mechanisms of childhood-onset bipolar disorder may assist in the development of future targeted, effective therapies.

Valproate Use in Women Who Could Become Pregnant: The Argument for Informed Consent

Valproate Use in Women Who Could Become Pregnant: The Argument for Informed Consent

By

There is currently no international agreement on the appropriate regulation of valproate in people who may become pregnant.

Circadian Rhythm Disruptions Associated With Mood Disorders, Adverse Quality of Life

Circadian Rhythm Disruptions Associated With Mood Disorders, Adverse Quality of Life

By

This study had a sample size large enough to assess the effect of circadian disruption on mental health disorders, and was the first to objectively measure patterns of rest and activity (using accelerometers).

Smartphone-Based Monitoring for Bipolar Depression, Mania Symptoms: Results From MONARCA II Trial

Smartphone-Based Monitoring for Bipolar Depression, Mania Symptoms: Results From MONARCA II Trial

By

The primary outcomes assessed were the differences in clinically assessed depressive and manic symptoms, as well as the rate of depressive and manic episodes.

Neurocognitive Profile in Comorbid OCD and Bipolar Disorder

Neurocognitive Profile in Comorbid OCD and Bipolar Disorder

By

Investigators compared set-shifting, decision making, and central coherence in patients with bipolar disorder, OCD, and comorbid bipolar disorder with OCD.

Social Cognition May Moderate Neurocognition, Community Functioning in Bipolar Disorder

Social Cognition May Moderate Neurocognition, Community Functioning in Bipolar Disorder

By

These findings indicate a significant modulative effect of social cognition on neurocognition and community functioning in bipolar disorder and thus may be relevant in titrating treatment in patients with varying social cognition levels.

Psychiatric Comorbidities Increase Neurologic Disability in Multiple Sclerosis

Psychiatric Comorbidities Increase Neurologic Disability in Multiple Sclerosis

By

Patients with MS and comorbid psychiatric conditions have increased severity of subsequent neurological disability.

Personality Functioning Associated With Global Functioning in Bipolar Disorder I

Personality Functioning Associated With Global Functioning in Bipolar Disorder I

By

These results highlight the potential utility of incorporating personality functioning assessments into bipolar disorder I treatment plans to fully restore global functioning during remission.

GDF-15 Levels: Examining Premature Aging in Bipolar Disorder

GDF-15 Levels: Examining Premature Aging in Bipolar Disorder

By

Researchers noted that therapeutic interventions focused on GDF-15 levels may decrease mortality risk and increase longevity in patients with bipolar disorder.

Family-Focused Intervention Effective for Caregivers of Patients With Bipolar Disorder

Family-Focused Intervention Effective for Caregivers of Patients With Bipolar Disorder

By

Patients associated with caregivers who received family-focused treatment also demonstrated a significant decrease in depressive symptoms compared with patients associated with caregivers in the control group.

Incidence of Psychiatric Disorders in Rheumatoid Arthritis

Incidence of Psychiatric Disorders in Rheumatoid Arthritis

By

The incidence and prevalence of psychiatric disorders such as depression, anxiety, and bipolar disorder are higher in the rheumatoid arthritis population.

Examining Rates of Conversion From Unipolar Depression to Bipolar Disorder

Examining Rates of Conversion From Unipolar Depression to Bipolar Disorder

By

Making mental health predictions based on clinical presentation has major limitations.

Bipolar Disorder Symptoms Lessened by Cognitive-Behavioral Therapy

Bipolar Disorder Symptoms Lessened by Cognitive-Behavioral Therapy

By

CBT is effective in patients with bipolar disorder in decreasing the relapse rate and improving symptoms of depression and mania severity.

Does Methylphenidate Lead to Treatment-Emergent Mania?

Does Methylphenidate Lead to Treatment-Emergent Mania?

By

Patients with comorbid bipolar disorder and ADHD may benefit from methylphenidate treatment, if it can be done without incurring the risk of mania.

Searching for Novel Endophenotypic Markers for Bipolar Disorder

Searching for Novel Endophenotypic Markers for Bipolar Disorder

By

Intra-subject variability in reaction time (ISVRT) is viewed as a promising behavioral endophenotype for bipolar disorder.

Brain-derived Neurotrophic Factor and its Precursor proBDNF as Diagnostic Biomarkers for Mood Disorders

Brain-derived Neurotrophic Factor and its Precursor proBDNF as Diagnostic Biomarkers for Mood Disorders

By

mBDNF/proBDNF ratio could potentially serve as a novel biomarker for mood disorders.

6-minute Walk Test Offers Insight Into Global Functioning Among Patients With Bipolar Disorder

6-minute Walk Test Offers Insight Into Global Functioning Among Patients With Bipolar Disorder

By

Until now, assessment of aerobic exercise capacity included expensive and time-consuming laboratory tests that do not necessarily accurately reflect patients' day-to-day physical functioning.

Irritability in Recovered Bipolar Disorder Patients Linked to Greater Morbidity, Depression Recurrence

Irritability in Recovered Bipolar Disorder Patients Linked to Greater Morbidity, Depression Recurrence

By

Delayed depressive recovery occurred more in depressed patients with current irritability.

Cognition and White Matter Alterations in Schizophrenia, Bipolar Disorder

Cognition and White Matter Alterations in Schizophrenia, Bipolar Disorder

By

Direct comparison of white matter tracts between individuals with schizophrenia or bipolar disorder has not been performed to date.

Psychosocial and Demographic Predictors of Depression Among Individuals With Bipolar Disorder and Schizophrenia

Psychosocial and Demographic Predictors of Depression Among Individuals With Bipolar Disorder and Schizophrenia

By

Bipolar disorder and schizophrenia are characterized by significant genetic overlap, as well as significant clinical presentation overlap.

Cortical Molecular Markers Differentiate Psychotic, Bipolar Disorders

Cortical Molecular Markers Differentiate Psychotic, Bipolar Disorders

By

The researchers quantified the transcript levels of GAD67, parvalbumin, somastatin, and Lhx6 in the prefrontal cortex.

Bipolar Disorder Linked With Gene Expression in Unexpected Brain Region

Bipolar Disorder Linked With Gene Expression in Unexpected Brain Region

By

New findings underline the potential importance of signaling pathways in the striatum for understanding bipolar disorder pathophysiology.

Exposure to Stressful Triggers Increases Risk for Violent Criminality Irrespective of Psychiatric Condition

Exposure to Stressful Triggers Increases Risk for Violent Criminality Irrespective of Psychiatric Condition

By

The largest 7-day absolute risk of criminal violence was observed after exposure to violence in patients diagnosed with schizophrenia, bipolar disorder, as well as in unaffected individuals.

Sign Up for Free e-newsletters