Bipolar Disorder

Monetary Incentives Improve Cessation in Mentally Ill Smokers

Monetary Incentives Improve Cessation in Mentally Ill Smokers

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Abstinence-contingent incentives improved smoking cessation outcomes among economically disadvantaged smokers with mental illness.

Bipolar Disorder, Borderline Personality Disorder May Represent the Same Disorder

Bipolar Disorder, Borderline Personality Disorder May Represent the Same Disorder

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Bipolar disorder and borderline personality disorder reflect alternate expressions of the same underlying disorder.

Benefits of Psychoeducation in Bipolar Disorder Mediated by Perceived Improvement

Benefits of Psychoeducation in Bipolar Disorder Mediated by Perceived Improvement

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The benefits of psychoeducation for patients with bipolar disorder were mediated by perceived change in illness.

Residual Anxiety Predicts Depression Relapse in Bipolar II Depression

Residual Anxiety Predicts Depression Relapse in Bipolar II Depression

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Venlafaxine was superior to lithium in reducing symptoms of both bipolar II depression and anxiety.

Association of Schizophrenia-Related Polygenic-Risk Score Across Bipolar Disorder Subtypes

Association of Schizophrenia-Related Polygenic-Risk Score Across Bipolar Disorder Subtypes

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A schizophrenia-related polygenic-risk score association gradient was identified across bipolar disorder phenotypes.

Psychotic Symptom Severity in BPAD Inversely Linked to Lithium Response

Psychotic Symptom Severity in BPAD Inversely Linked to Lithium Response

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The severity of psychotic symptoms in patients with bipolar affective disorder correlated inversely with the response to lithium therapy.

Predictors of Aggression in Patients With Bipolar Disorder, Schizophrenia

Predictors of Aggression in Patients With Bipolar Disorder, Schizophrenia

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Patients with schizophrenia-spectrum disorders had higher odds of being aggressive than people with bipolar disorder with a recent manic episode.

FDA Approves Schizophrenia Medication With Digital Ingestion Sensor

FDA Approves Schizophrenia Medication With Digital Ingestion Sensor

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The ability to track ingestion of medications prescribed for mental illness may be useful for some patients.

No Association Between Comorbid Anxiety Disorders, Suicide Attempts

No Association Between Comorbid Anxiety Disorders, Suicide Attempts

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Comorbid anxiety disorders among patients with depression or bipolar disorder were not associated with suicide attempts.

Lurasidone Reduces Depression in Children With Bipolar Disorder

Lurasidone Reduces Depression in Children With Bipolar Disorder

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Researchers evaluated the safety and efficacy of lurasidone in children and adolescents with bipolar depression.

Computerized Cognitive Remediation Improves Cognition in Bipolar Disorder

Computerized Cognitive Remediation Improves Cognition in Bipolar Disorder

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Inclusion of supportive elements such as rehabilitation may help drive translation of cognitive improvements to broad functional measures.

Elevated Dopamine Synthesis Capacity Observed in Both Bipolar and Schizophrenia

Elevated Dopamine Synthesis Capacity Observed in Both Bipolar and Schizophrenia

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Dopamine dysfunction underlies the pathoetiology of psychosis in both bipolar disorder and schizophrenia.

Asenapine Prevents Recurrence of Mood Events in Bipolar Disorder

Asenapine Prevents Recurrence of Mood Events in Bipolar Disorder

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Asenapine decreases the time to recurrence of manic and depressive episodes among patients with bipolar I disorder.

Bipolar Depression Benefits From Midday Bright Light Therapy

Bipolar Depression Benefits From Midday Bright Light Therapy

Bright light therapy might be effective for the treatment of bipolar depression.

ADHD, Comorbid Bipolar Disorder Share Similar Neurocognitive Profiles

ADHD, Comorbid Bipolar Disorder Share Similar Neurocognitive Profiles

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People with both bipolar disorder and ADHD have similar neurocognitive profiles compared with people with only bipolar disorder.

Olanzapine Effective in Treating Severe Mania Symptoms

Olanzapine Effective in Treating Severe Mania Symptoms

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Olanzapine was shown to be effective among patients with acute mania associated with bipolar I disorder.

Lithium Reduces Risk of Suicide in Patients With Mood Disorders

Lithium Reduces Risk of Suicide in Patients With Mood Disorders

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Lithium is the only medication to demonstrate an antisuicidal effect over and above its action on mood episodes in bipolar disorder.

Bipolar Disorder Therapy Response Possibly Impeded by Proinflammatory State

Bipolar Disorder Therapy Response Possibly Impeded by Proinflammatory State

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An M1-like proinflammatory state is associated with a poor response to antidepressant treatment in bipolar depression with evidence suggesting increased production of cytokines in patients with mood disorders.

Juvenile Bipolar Disorder: Intranasal Ketamine Effective, Well-Tolerated

Juvenile Bipolar Disorder: Intranasal Ketamine Effective, Well-Tolerated

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Ketamine improves social function and academic performance in juvenile patients with bipolar disorder with a fear of harm phenotype.

Antipsychotic Reduction in Bipolar Disorder, Depression: Higher Healthcare Burden

Antipsychotic Reduction in Bipolar Disorder, Depression: Higher Healthcare Burden

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For patients with bipolar disorder and major depressive disorder, reduction in dose of antipsychotic medication could lead to an increased rate of hospitalization.

Effect of Mixed State on Suicidal Behavior in Patients With Bipolar Disorder

Effect of Mixed State on Suicidal Behavior in Patients With Bipolar Disorder

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Mixed state does not increase the risk for suicidal behavior beyond the risk associated with the depressive component.

Psychosis Not Associated With Bipolar Disorder Severity

Psychosis Not Associated With Bipolar Disorder Severity

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Psychosis in patients with bipolar disorder was not associated with worse clinical or functional outcomes.

Increased Psychotic Symptoms in Offspring of Patients With Schizophrenia

Increased Psychotic Symptoms in Offspring of Patients With Schizophrenia

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Children and adolescent offspring of patients with schizophrenia demonstrate more attenuated psychotic symptoms.

New Model Shows High Accuracy in Predicting Response to Lithium

New Model Shows High Accuracy in Predicting Response to Lithium

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Lithium response may be predicted with better accuracy by a new model.

Long-term Response to Prophylactic Mood Stabilizers in Bipolar Disorder

Long-term Response to Prophylactic Mood Stabilizers in Bipolar Disorder

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Mixed and psychotic features and comorbid anxiety disorder were associated with poor treatment response in bipolar disorder.

Risk of Mood Disorders Increased From Sugary Beverages, Foods

Risk of Mood Disorders Increased From Sugary Beverages, Foods

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The risk for mood disorders increases with the more sugar consumed from beverages and food.

Youth With BD Do Not Experience Cognitive Decline Into Adulthood

Youth With BD Do Not Experience Cognitive Decline Into Adulthood

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Bipolar disorder in youth does not exhibit a cognitive worsening over time.

Bipolar Disorder: Childhood Trauma Modulates Impact on Amygdala, Hippocampus

Bipolar Disorder: Childhood Trauma Modulates Impact on Amygdala, Hippocampus

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Childhood trauma modulates the effects of bipolar disorder on the amygdala and hippocampus by causing an increase in the volumes of gray matter.

FDA Approves Abilify Maintena for Bipolar I Disorder Monotherapy Treatment

FDA Approves Abilify Maintena for Bipolar I Disorder Monotherapy Treatment

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New bipolar I disorder treatment Abilify Maintena is only required once a month.

Bipolar Disorder in Pregnant Women Not Improved by Psychotropic Medications

Bipolar Disorder in Pregnant Women Not Improved by Psychotropic Medications

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Pregnant women with bipolar disorder receiving psychotropic medication did not experience less functional impairment and symptom burden.

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