Bipolar Disorder

Lurasidone May Be Effective for Long-Term Treatment of Pediatric Bipolar Depression

Lurasidone May Be Effective for Long-Term Treatment of Pediatric Bipolar Depression

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In pediatric patients with bipolar I depression, long-term treatment with lurasidone 20 mg/day is effective in reducing depressive symptoms.

Neurocognitive Profile in Comorbid OCD and Bipolar Disorder

Neurocognitive Profile in Comorbid OCD and Bipolar Disorder

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Investigators compared set-shifting, decision making, and central coherence in patients with bipolar disorder, OCD, and comorbid bipolar disorder with OCD.

Social Cognition May Moderate Neurocognition, Community Functioning in Bipolar Disorder

Social Cognition May Moderate Neurocognition, Community Functioning in Bipolar Disorder

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These findings indicate a significant modulative effect of social cognition on neurocognition and community functioning in bipolar disorder and thus may be relevant in titrating treatment in patients with varying social cognition levels.

Children of Consanguineous Marriage at Increased Risk for Mood Disorders, Psychoses

Children of Consanguineous Marriage at Increased Risk for Mood Disorders, Psychoses

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Communities that favor consanguineous marriage should receive sensitive advice on the risks involved to aid in reproductive decision making.

Personality Functioning Associated With Global Functioning in Bipolar Disorder I

Personality Functioning Associated With Global Functioning in Bipolar Disorder I

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These results highlight the potential utility of incorporating personality functioning assessments into bipolar disorder I treatment plans to fully restore global functioning during remission.

GDF-15 Levels: Examining Premature Aging in Bipolar Disorder

GDF-15 Levels: Examining Premature Aging in Bipolar Disorder

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Researchers noted that therapeutic interventions focused on GDF-15 levels may decrease mortality risk and increase longevity in patients with bipolar disorder.

Family-Focused Intervention Effective for Caregivers of Patients With Bipolar Disorder

Family-Focused Intervention Effective for Caregivers of Patients With Bipolar Disorder

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Patients associated with caregivers who received family-focused treatment also demonstrated a significant decrease in depressive symptoms compared with patients associated with caregivers in the control group.

Addressing Racial Disparities in Bipolar Disorder Treatment

Addressing Racial Disparities in Bipolar Disorder Treatment

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Individuals of African ancestry are more likely misdiagnosed with a disease other than bipolar disorder.

Predicting Treatment-Emergent Mania to Tailor Pharmacotherapy in Bipolar Disorder

Predicting Treatment-Emergent Mania to Tailor Pharmacotherapy in Bipolar Disorder

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Researchers characterized the psychopathological features in patients with type II bipolar disorder who experienced treatment-emergent mania after exposure to antidepressants.

Recent-Onset Bipolar Disorder Associated With Higher Fasting Triglyceride Levels

Recent-Onset Bipolar Disorder Associated With Higher Fasting Triglyceride Levels

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Patients with type I bipolar disorder had significantly higher fasting triglyceride levels (121.7 mg/dL vs 87.0 mg/dL, P <.01).

Interepisode Residual Depressive Symptoms Affect Course of Bipolar Disorder

Interepisode Residual Depressive Symptoms Affect Course of Bipolar Disorder

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Individuals with depressive residual symptoms between episodes may have more of a negative course of illness.

Manic Switching After Light Therapy Historically Low in Bipolar Disorder

Manic Switching After Light Therapy Historically Low in Bipolar Disorder

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These findings challenge existing concerns about the association of light therapy with manic switching and may be useful for clinicians in developing treatment strategies for patients with bipolar disorder.

Emergency Mental Health Services During Hurricane Harvey: Challenges and Lessons

Emergency Mental Health Services During Hurricane Harvey: Challenges and Lessons

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Bipolar disorder (31.9%), depression (19.8%), schizophrenia (14.2%), and anxiety disorders (9.1%) were the most common mental health issues reported. Approximately 13% of evacuees with a mental health concern reported a history of post-traumatic stress disorder.

A Slow Road Toward Personalized Treatment of Bipolar Disorder

A Slow Road Toward Personalized Treatment of Bipolar Disorder

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Successful management of both the manic and depressive states in bipolar disorder has been difficult to achieve, despite a broad range of pharmacologic treatments available.

Probing the Link Between Mood Disorders and Lithium in Water Supplies

Probing the Link Between Mood Disorders and Lithium in Water Supplies

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Michael Thase, MD, comments on the potential for lithium in drinking water as a psychiatric prophylactic agent.

Psychosis Associated With Increased Complications Following Total Joint Arthroplasty

Psychosis Associated With Increased Complications Following Total Joint Arthroplasty

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Investigators seek the association between psychosis and complication risk after total joint arthroplasty.

Exploring Safe and Effective Treatments for Bipolar Depression: Transcranial Direct Current Stimulation

Exploring Safe and Effective Treatments for Bipolar Depression: Transcranial Direct Current Stimulation

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Transcranial direct current stimulation may be an effective add-on treatment for bipolar depression.

Managing Comorbid Bipolar Disorder and Alcohol Use Disorder: Clinical Challenges and Conundrums

Managing Comorbid Bipolar Disorder and Alcohol Use Disorder: Clinical Challenges and Conundrums

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The frequent comorbidity of bipolar disorder and alcohol use disorder presents a significant challenge for clinicians managing patients with these conditions.

Lurasidone Monotherapy Safe, Efficacious in Children, Adolescents With Bipolar Depression

Lurasidone Monotherapy Safe, Efficacious in Children, Adolescents With Bipolar Depression

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Safety and efficacy of lurasidone monotherapy were assessed in children and adolescents with bipolar I depression.

Pregnancy and Bipolar Disorder: Expert Interview With Leena Mittal, MD

Pregnancy and Bipolar Disorder: Expert Interview With Leena Mittal, MD

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The Oregon Foundation for Reproductive Health recommends that all medical providers ask all female patients of reproductive age if they plan to become pregnant in the next year.

Neurocognitive Function Improved After 1 Year in Non-Relapsing Bipolar I Disorder

Neurocognitive Function Improved After 1 Year in Non-Relapsing Bipolar I Disorder

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Patients with bipolar I disorder without relapse after 1 year of first treatment had improved neurocognitive functioning.

Monetary Incentives Improve Cessation in Mentally Ill Smokers

Monetary Incentives Improve Cessation in Mentally Ill Smokers

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Abstinence-contingent incentives improved smoking cessation outcomes among economically disadvantaged smokers with mental illness.

Bipolar Disorder, Borderline Personality Disorder May Represent the Same Disorder

Bipolar Disorder, Borderline Personality Disorder May Represent the Same Disorder

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Bipolar disorder and borderline personality disorder reflect alternate expressions of the same underlying disorder.

Benefits of Psychoeducation in Bipolar Disorder Mediated by Perceived Improvement

Benefits of Psychoeducation in Bipolar Disorder Mediated by Perceived Improvement

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The benefits of psychoeducation for patients with bipolar disorder were mediated by perceived change in illness.

Residual Anxiety Predicts Depression Relapse in Bipolar II Depression

Residual Anxiety Predicts Depression Relapse in Bipolar II Depression

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Venlafaxine was superior to lithium in reducing symptoms of both bipolar II depression and anxiety.

Association of Schizophrenia-Related Polygenic-Risk Score Across Bipolar Disorder Subtypes

Association of Schizophrenia-Related Polygenic-Risk Score Across Bipolar Disorder Subtypes

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A schizophrenia-related polygenic-risk score association gradient was identified across bipolar disorder phenotypes.

Psychotic Symptom Severity in BPAD Inversely Linked to Lithium Response

Psychotic Symptom Severity in BPAD Inversely Linked to Lithium Response

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The severity of psychotic symptoms in patients with bipolar affective disorder correlated inversely with the response to lithium therapy.

Predictors of Aggression in Patients With Bipolar Disorder, Schizophrenia

Predictors of Aggression in Patients With Bipolar Disorder, Schizophrenia

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Patients with schizophrenia-spectrum disorders had higher odds of being aggressive than people with bipolar disorder with a recent manic episode.

FDA Approves Schizophrenia Medication With Digital Ingestion Sensor

FDA Approves Schizophrenia Medication With Digital Ingestion Sensor

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The ability to track ingestion of medications prescribed for mental illness may be useful for some patients.

No Association Between Comorbid Anxiety Disorders, Suicide Attempts

No Association Between Comorbid Anxiety Disorders, Suicide Attempts

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Comorbid anxiety disorders among patients with depression or bipolar disorder were not associated with suicide attempts.

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