Bipolar 2017

FDA Approves Schizophrenia Medication With Digital Ingestion Sensor

FDA Approves Schizophrenia Medication With Digital Ingestion Sensor

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The ability to track ingestion of medications prescribed for mental illness may be useful for some patients.

No Association Between Comorbid Anxiety Disorders, Suicide Attempts

No Association Between Comorbid Anxiety Disorders, Suicide Attempts

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Comorbid anxiety disorders among patients with depression or bipolar disorder were not associated with suicide attempts.

Computerized Cognitive Remediation Improves Cognition in Bipolar Disorder

Computerized Cognitive Remediation Improves Cognition in Bipolar Disorder

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Inclusion of supportive elements such as rehabilitation may help drive translation of cognitive improvements to broad functional measures.

Elevated Dopamine Synthesis Capacity Observed in Both Bipolar and Schizophrenia

Elevated Dopamine Synthesis Capacity Observed in Both Bipolar and Schizophrenia

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Dopamine dysfunction underlies the pathoetiology of psychosis in both bipolar disorder and schizophrenia.

Asenapine Prevents Recurrence of Mood Events in Bipolar Disorder

Asenapine Prevents Recurrence of Mood Events in Bipolar Disorder

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Asenapine decreases the time to recurrence of manic and depressive episodes among patients with bipolar I disorder.

ADHD, Comorbid Bipolar Disorder Share Similar Neurocognitive Profiles

ADHD, Comorbid Bipolar Disorder Share Similar Neurocognitive Profiles

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People with both bipolar disorder and ADHD have similar neurocognitive profiles compared with people with only bipolar disorder.

Olanzapine Effective in Treating Severe Mania Symptoms

Olanzapine Effective in Treating Severe Mania Symptoms

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Olanzapine was shown to be effective among patients with acute mania associated with bipolar I disorder.

Bipolar Disorder Therapy Response Possibly Impeded by Proinflammatory State

Bipolar Disorder Therapy Response Possibly Impeded by Proinflammatory State

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An M1-like proinflammatory state is associated with a poor response to antidepressant treatment in bipolar depression with evidence suggesting increased production of cytokines in patients with mood disorders.

Juvenile Bipolar Disorder: Intranasal Ketamine Effective, Well-Tolerated

Juvenile Bipolar Disorder: Intranasal Ketamine Effective, Well-Tolerated

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Ketamine improves social function and academic performance in juvenile patients with bipolar disorder with a fear of harm phenotype.

Antipsychotic Reduction in Bipolar Disorder, Depression: Higher Healthcare Burden

Antipsychotic Reduction in Bipolar Disorder, Depression: Higher Healthcare Burden

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For patients with bipolar disorder and major depressive disorder, reduction in dose of antipsychotic medication could lead to an increased rate of hospitalization.

Effect of Mixed State on Suicidal Behavior in Patients With Bipolar Disorder

Effect of Mixed State on Suicidal Behavior in Patients With Bipolar Disorder

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Mixed state does not increase the risk for suicidal behavior beyond the risk associated with the depressive component.

Psychosis Not Associated With Bipolar Disorder Severity

Psychosis Not Associated With Bipolar Disorder Severity

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Psychosis in patients with bipolar disorder was not associated with worse clinical or functional outcomes.

Increased Psychotic Symptoms in Offspring of Patients With Schizophrenia

Increased Psychotic Symptoms in Offspring of Patients With Schizophrenia

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Children and adolescent offspring of patients with schizophrenia demonstrate more attenuated psychotic symptoms.

New Model Shows High Accuracy in Predicting Response to Lithium

New Model Shows High Accuracy in Predicting Response to Lithium

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Lithium response may be predicted with better accuracy by a new model.

Bipolar Disorder: Childhood Trauma Modulates Impact on Amygdala, Hippocampus

Bipolar Disorder: Childhood Trauma Modulates Impact on Amygdala, Hippocampus

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Childhood trauma modulates the effects of bipolar disorder on the amygdala and hippocampus by causing an increase in the volumes of gray matter.

FDA Approves Abilify Maintena for Bipolar I Disorder Monotherapy Treatment

FDA Approves Abilify Maintena for Bipolar I Disorder Monotherapy Treatment

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New bipolar I disorder treatment Abilify Maintena is only required once a month.

Bipolar Disorder in Pregnant Women Not Improved by Psychotropic Medications

Bipolar Disorder in Pregnant Women Not Improved by Psychotropic Medications

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Pregnant women with bipolar disorder receiving psychotropic medication did not experience less functional impairment and symptom burden.

Bipolar Spectrum Disorder in Youth Predicted By New Risk Calculator

Bipolar Spectrum Disorder in Youth Predicted By New Risk Calculator

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Bipolar disorder probability in the offspring of a parent with BP was assessed by a risk calculator.

Better Outcomes With Lithium vs Quetiapine for Early Manic Episodes of Bipolar Disorder

Better Outcomes With Lithium vs Quetiapine for Early Manic Episodes of Bipolar Disorder

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Australian investigators found significant differences in early results from different treatments for bipolar disorder.

Analysis of Cognitive Impairment Tx Strategies in Bipolar Disorder

Analysis of Cognitive Impairment Tx Strategies in Bipolar Disorder

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In bipolar disorder, neurocognitive impairment needs to be considered a therapeutic clinical target to improve psychosocial functioning.

Thyroid Disease Linked With Higher Rates of Manic Relapse In Bipolar Disorder

Thyroid Disease Linked With Higher Rates of Manic Relapse In Bipolar Disorder

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Manic relapse in bipolar disorder is connected to thyroid disease.

Bipolar Disorder Relapse Episodes Delayed With Risperidone Treatment

Bipolar Disorder Relapse Episodes Delayed With Risperidone Treatment

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Bipolar disorder mood relapse episodes were delayed with risperidone long-acting injection.

Lamotrigine: Alternate Bipolar Disorder Treatment to Lithium During Pregnancy

Lamotrigine: Alternate Bipolar Disorder Treatment to Lithium During Pregnancy

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Bipolar disorder treatment with lamotrigine during pregnancy may also prevent postpartum depressive episodes.

Correct Bipolar Disorder Diagnosis Delayed By Depression Diagnosis At Younger Age

Correct Bipolar Disorder Diagnosis Delayed By Depression Diagnosis At Younger Age

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Depressed patients with diagnoses that ultimately converted to bipolar disorder had been diagnosed with depression earlier.

Depression Treatment May Benefit from Use of Ketamine

Depression Treatment May Benefit from Use of Ketamine

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Ketamine can provide acute benefits for treatment-resistant depression, bipolar depression, and major depressive disorder with suicidal ideation.

Lithium Not Associated With Increased Cancer Risk in Bipolar Disorder

Lithium Not Associated With Increased Cancer Risk in Bipolar Disorder

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Neither bipolar disorder nor lithium treatment was associated with increased cancer incidence.

Quetiapine-XR Effective on Depressive Symptoms, Substance Use Disorder

Quetiapine-XR Effective on Depressive Symptoms, Substance Use Disorder

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Quetiapine-XR may be effective in reducing substance abuse in patients with bipolar disorder.

Early Bipolar Depression Response to Lurasidone Treatment

Early Bipolar Depression Response to Lurasidone Treatment

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Bipolar depression treatment response to lurasidone between baseline and week 2 indicates later treatment success.

Bipolar Disorder Symptoms Lessened by Cognitive-Behavioral Therapy

Bipolar Disorder Symptoms Lessened by Cognitive-Behavioral Therapy

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CBT is effective in patients with bipolar disorder in decreasing the relapse rate and improving symptoms of depression and mania severity.

Greater Cognitive Decline in Individuals at Risk for Bipolar Disorder With Obesity

Greater Cognitive Decline in Individuals at Risk for Bipolar Disorder With Obesity

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The burden of illness associated with bipolar disorder warrants early preemption.

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