Antipsychotic

Personalized Treatment With Second vs. First Generation Antipsychotics

Personalized Treatment With Second vs. First Generation Antipsychotics

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The primary outcome in this study was the change in total quality-of-life scores from baseline to week 24 after patients were randomly assigned to a treatment group.

Psychosis Treatments

A comparative dosing and titration chart of commonly used first-generation and second-generation antipsychotics.

FDA Warning: Antipsychotic Linked to Impulse-Control Problems

FDA Warning: Antipsychotic Linked to Impulse-Control Problems

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The FDA has mandated new warnings to include a list of compulsive behaviors.

Atypical Antipsychotic Pharmacokinetics

A chart outlining the pharmacokinetics of atypical antipsychotics, including information on bioavailability, half-life and CYP 450 metabolism.

E-prescribing Linked With Fewer Medication Errors and Adverse Effects

E-prescribing Linked With Fewer Medication Errors and Adverse Effects

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For practitioners who are interested in implementing an e-prescribing system, Dr Hurford suggests that they seek feedback from colleagues.

Antipsychotics Ineffective for Delirium During Hospitalization

Antipsychotics Ineffective for Delirium During Hospitalization

No significant effect was found for preventing or treating delirium during hospitalization with antipsychotic medications.

Teens With Autism At Higher Risk of Type 2 Diabetes

Teens With Autism At Higher Risk of Type 2 Diabetes

Those taking atypical antipsychotics also showed a higher risk of developing type 2 diabetes.

Patients on Antipsychotics Rarely Screened for Diabetes

Patients on Antipsychotics Rarely Screened for Diabetes

70% of severely mentally ill patients on Medicaid were not tested for diabetes, despite having a two to three times greater risk.

Long-Term Antipsychotic Use Common in Alzheimer's Patients

Long-Term Antipsychotic Use Common in Alzheimer's Patients

Guidelines, however, say that antipsychotics should only be used short term for severe psychotic symptoms and agitation.

FDA Approves New Long-Acting Antipsychotic

FDA Approves New Long-Acting Antipsychotic

Aristada (aripiprazole lauroxil) is injected every four-to-six weeks.

Treating Parkinson's Psychosis With Antipsychotics May Boost Death Risk

Treating Parkinson's Psychosis With Antipsychotics May Boost Death Risk

PDP patients treated with antipsychotics were four times as likely to died following three to six months of treatment than those not on the meds.

Antipsychotic Plus Antidepressant Helps Treatment-Resistant Depression

Antipsychotic Plus Antidepressant Helps Treatment-Resistant Depression

44% of depressed participants who received the antipsychotic aripiprazole in addition to an antispychotic achieved remission.

First Generic of Antipsychotic Invega Available

First Generic of Antipsychotic Invega Available

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Generic versions of oral Invega (paliperidone) are available in 1.5m, 3mg, 6mg, and 9mg strength extended-release tablets.

Majority of Dementia Patients Take Multiple Psychotropic Drugs

Majority of Dementia Patients Take Multiple Psychotropic Drugs

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Dementia patients who were younger, female and lived in nursing homes were most associated with psychotropic polypharmacy.

FDA Approves New Schizophrenia, Depression Drug Brexpiprazole

FDA Approves New Schizophrenia, Depression Drug Brexpiprazole

Rexulti (brexpiprazole), from Otsuka and Lundbeck, is approved as a monotherapy in schizophrenia and an adjunct in patients with major depression.

Smoking May Boost Psychosis Risk

Smoking May Boost Psychosis Risk

Almost 60% of people diagnosed with a first episode of psychosis were also smokers.

FDA Issues Warning About Counterfeit Benzodiazepine Sold Online

FDA Issues Warning About Counterfeit Benzodiazepine Sold Online

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WHO identifies over 700 adverse event reports from Africa of patients taking what they thought was diazepam but was actually haloperidol.

Lowering Antipsychotic Dose Safe For Older Schizophrenia Patients

Lowering Antipsychotic Dose Safe For Older Schizophrenia Patients

Patients with late life schizophrenia who had their antipsychotic dose reduced had fewer side effects without sacrificing medication efficacy.

Use of Antipsychotics By Teens, Young Adults Rises

Use of Antipsychotics By Teens, Young Adults Rises

Males were more likely to be given antipsychotics than females, and among young adults given the drugs, depression was most common diagnosis.

Mortality Risk Increased for Parkinson's Patients on Antipsychotics

Mortality Risk Increased for Parkinson's Patients on Antipsychotics

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Parkinson's patients who took any antipsychotic were more than twice as likely to die within 180 days than those not on one.

First Three-Month-Long Injectable Antipsychotic Now Available

First Three-Month-Long Injectable Antipsychotic Now Available

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Invega Trinza is dosed once every four months following monthly treatment of Invega Sustenna for at least four months.

Declassifying Psychedelic Drugs to Examine Their Treatment Potential

Declassifying Psychedelic Drugs to Examine Their Treatment Potential

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One psychiatrist is calling on authorities to declassify psychedelic drugs to study their therapeutic potential for mental illnesses.

Long-Acting Injectable Antipsychotics Lead To Better Results Than Oral Versions

Long-Acting Injectable Antipsychotics Lead To Better Results Than Oral Versions

Patients taking a long-acting injectable antipsychotic had better medication adherence and control of symptoms than peers taking a pill version.

Patients, Psychiatrists Frustrated With Existing Schizophrenia Meds

Patients, Psychiatrists Frustrated With Existing Schizophrenia Meds

In survey, patients with schizophrenia and psychiatrists both expressed displeasure over efficacy and side effects of current antipsychotics.

Parkinson's Disease Psychosis: Common, Yet Not Often Reported

Parkinson's Disease Psychosis: Common, Yet Not Often Reported

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PD psychosis is underreported and faces treatment challenges, though a new treatment on the horizon may change that.

Avoid Antipsychotics As First-Line Insomnia Therapy, Groups Say

Avoid Antipsychotics As First-Line Insomnia Therapy, Groups Say

A group of psychiatric associations is recommending that behavioral changes and other nonpharmacological interventions be used instead.

Some Antipsychotics Linked to Weight Gain in Children

Some Antipsychotics Linked to Weight Gain in Children

However, researchers found no weight gain in children and adolescents who took SSRI and SNRI antidepressants.

Some Psychiatric Drugs May Be Linked to Higher Homicide Risk

Some Psychiatric Drugs May Be Linked to Higher Homicide Risk

An study of people convicted of homicides found that using benzodiazepines was associated with a 45% increased risk of doing so.

Experimental Schizophrenia Drug Shows Promise in Phase II

Experimental Schizophrenia Drug Shows Promise in Phase II

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A Phase II trial of Intra-Cellular's ITI-007 shows improvement in negative symptoms of schizophrenia without side effects seen in other antipsychotics.

FDA Approves First Three-Month-Long Injectable Antipsychotic

FDA Approves First Three-Month-Long Injectable Antipsychotic

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Invega Trinza, from Janssen, should be available to patients by mid-June.

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