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AMRIX
Muscle spasms
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Drug Name:

AMRIX Rx

Generic Name and Formulations:
Cyclobenzaprine HCl 15mg, 30mg; ext-rel caps.

Company:
Teva Pharmaceuticals

Therapeutic Use:

Indications for AMRIX:

Adjunct to rest and physical therapy for relief of muscle spasm associated with acute, painful musculoskeletal conditions.

Adult:

Take at same time each day. 15mg once daily; may increase to 30mg/day given once daily. Max 2–3 weeks. Elderly or hepatic impairment: not recommended.

Children:

Not established.

Contraindications:

Acute post-MI. Arrhythmias, heart block, other conduction disturbances. CHF. Hyperthyroidism. During or within 14 days of MAOIs.

Warnings/Precautions:

Not effective in treating spasticity associated with cerebral or spinal chord disease or in children with cerebral palsy. Urinary retention. Angle-closure glaucoma. Increased intraocular pressure. Hepatic impairment or elderly: not recommended. Pregnancy (Cat.B). Nursing mothers.

Interactions:

See Contraindications. Hypertensive crisis with MAOIs. Increased risk of serotonin syndrome with other serotonergic drugs (eg, SSRIs, SNRIs, tricyclic antidepressants, tramadol, bupropion, meperidine, verapamil, MAOIs); discontinue if occurs. Potentiates anticholinergics, alcohol, other CNS depressants. May antagonize guanethidine, clonidine. May enhance seizure risk with concomitant tramadol.

Pharmacological Class:

Muscle relaxant (central).

Adverse Reactions:

Drowsiness, dry mouth, dizziness, fatigue, headache, somnolence, constipation, nausea, dyspepsia, dysgeusia, tremor, nervousness, asthenia, blurred vision, confusion.

How Supplied:

Caps—60

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