Alzheimer's Disease

Gender-dependent Differences in Alzheimer Disease Diagnosis

Gender-dependent Differences in Alzheimer Disease Diagnosis

In 2016, an estimated 5.4 million US adults have Alzheimer disease.

Sundowning: Phenomenology, Pathophysiology, and Treatment Approaches

Sundowning: Phenomenology, Pathophysiology, and Treatment Approaches

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Sundowning is a complex multifactorial condition that has eluded rigorous understanding of its pathophysiological causes.

Deep Brain Stimulation Appears Safe in Alzheimer's

Deep Brain Stimulation Appears Safe in Alzheimer's

Participants aged ≥65 years may have derived benefit from stimulation, while there was possible worsening in patients below age 65 years.

Alzheimer Markers Detected in Healthy Individuals with Genetic AD Risk

Alzheimer Markers Detected in Healthy Individuals with Genetic AD Risk

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The effects of aggregate genetic AD risk are detectable before symptoms appear, even early in life.

CSF Biomarkers Improve Diagnosis in Patients with Psychiatric Disorders & Cognitive Symptoms

CSF Biomarkers Improve Diagnosis in Patients with Psychiatric Disorders & Cognitive Symptoms

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Distinguishing between psychiatric disorders and AD is crucial because of the differing prognosis and management of the two.

No Evidence for Transmission of Alzheimer Pathology Through Blood Transfusions

No Evidence for Transmission of Alzheimer Pathology Through Blood Transfusions

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If transmission of neurodegenerative diseases such as dementia of any type, AD, or PD does occur, it is rare.

Cannabinoids Reduce Intraneuronal Beta Amyloid Protein Levels

Cannabinoids Reduce Intraneuronal Beta Amyloid Protein Levels

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Tetrahydrocannabinol (THC) is the main active chemical ingredient found in cannabis and is a potent cannabinoid receptor (CB)-1 agonist.

Could Alzheimer's Disease be Caused by Infections?

Could Alzheimer's Disease be Caused by Infections?

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Although inconclusive, late-onset Alzheimer's Disease could be triggered by infectious pathogens.

Anti-Rejection Organ Transplant Drugs May Also Stave Off Alzheimer's

Anti-Rejection Organ Transplant Drugs May Also Stave Off Alzheimer's

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Patients who were taking tacrolimus or cyclosporine after organ transplant had significantly lower rates of Alzheimer's compared to general public.

Blood Type May Influence Risk of Cognitive Decline, Alzheimer's

Blood Type May Influence Risk of Cognitive Decline, Alzheimer's

Individuals with type 'O' blood had more grey matter, thought to stave off cognitive decline, in their brains than other blood types.

Direct Link Found Between Toxic Alzheimer's Protein and Memory Loss

Direct Link Found Between Toxic Alzheimer's Protein and Memory Loss

The appearance of beta-amyloid plaque can rob memories in healthy brains before physical signs of neurocognitive degeneration appear in brain.

Some Alzheimer's Patients Have Increased Pain Sensitivity

Some Alzheimer's Patients Have Increased Pain Sensitivity

Patients with mild-to-moderate Alzheimer's and Parkinson's tended to experience more pain, yet those with other forms of cognitive impairment had less.

Damage To Brain's White Matter Could Be Early Alzheimer's Sign

Damage To Brain's White Matter Could Be Early Alzheimer's Sign

In early-onset and atypical forms of Alzheimer's, white matter degeneration could be an early biomarker prior to advancement of the disease.

Popular Alzheimer's Drug Namenda IR to Remain On the Market

Popular Alzheimer's Drug Namenda IR to Remain On the Market

A recent decision by a federal court has thwarted Actavis' alleged attempt to switch patients to Namenda XR prior to Namenda IR generics hitting market.

Omega-3 Fatty Acids May Aid Seniors At Risk For Alzheimer's

Omega-3 Fatty Acids May Aid Seniors At Risk For Alzheimer's

Seniors who consumed more Omega-3 fatty acids performed better on tests measuring cognitive flexibility.

Healthy Eating Lowers Risk of Cognitive Decline

Healthy Eating Lowers Risk of Cognitive Decline

Study involving more than 28,000 people in 40 countries finds those who scored highest on "healthy eating" index less likely to have memory decline.

First Symptoms of Alzheimer's Disease Vary By Age

First Symptoms of Alzheimer's Disease Vary By Age

Memory problems much more common in patients diagnosed with Alzheimer's at an older age.

Challenging Jobs May Help Some Dementia Patients Live Longer

Challenging Jobs May Help Some Dementia Patients Live Longer

People with frontotemporal dementia who had challenging jobs survived an average of 3.6 years longer than those with less challenging jobs.

Treating Sleep Disorders in Alzheimer's Patients

Treating Sleep Disorders in Alzheimer's Patients

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Nonpharmacologic interventions should be used first before medication to promote sleep is considered.

Sleep Apnea May Lead to Cognitive Impairment, Alzheimer's

Sleep Apnea May Lead to Cognitive Impairment, Alzheimer's

However, treatment with a CPAP machine in patients with sleep apnea delayed onset of cognitive impairment.

Can Milk Improve Brain Health and Prevent Alzheimer's?

Can Milk Improve Brain Health and Prevent Alzheimer's?

People who drank a lot of milk had higher levels of the antioxidant glutathione, which is known to have protective properties for the brain.

Antipsychotics Linked to Higher Mortality Risk in Dementia Patients

Antipsychotics Linked to Higher Mortality Risk in Dementia Patients

In seniors taking newer antipsychotics, risk of premature death increased with the dose.

Skin Test Could Help Diagnose Alzheimer's, Parkinson's

Skin Test Could Help Diagnose Alzheimer's, Parkinson's

Skin biopsies can reveal high levels of abnormal proteins linked to Alzheimer's and Parkinson's.

Type 2 Diabetes May Increase Risk for Alzheimer's

Type 2 Diabetes May Increase Risk for Alzheimer's

The formation of amyloid deposits in the pancreas can spread to the brain, leading to Alzheimer's.

Starting Football Young Increases Risk for Cognitive Deficits Later

Starting Football Young Increases Risk for Cognitive Deficits Later

Former pros who played before age of 11 show greater deficits in memory and thinking skills

Beer Ingredient May Slow Alzheimer's, Parkinson's Development

Beer Ingredient May Slow Alzheimer's, Parkinson's Development

A compound in the hops of beer may protect brain cells from damage that causes neurodegenerative diseases.

Depression, Anxiety May Precede Memory Loss in Alzheimer's

Depression, Anxiety May Precede Memory Loss in Alzheimer's

Depression, anxiety and sleep changes seen in middle-aged people prior to developing dementia symptoms.

Vascular Conditions, Stroke May Contribute to Alzheimer's Disease

Vascular Conditions, Stroke May Contribute to Alzheimer's Disease

More research on the link between vascular conditions, Alzheimer's disease, and dementia can help identify new treatments and preventions.

Virtual Reality Games Can Screen for Mild Cognitive Impairment

Virtual Reality Games Can Screen for Mild Cognitive Impairment

Virtual reality games can identify mild cognitive impairment with accuracy similar to neuropsychological tests.

Running May Lower Alzheimer's Mortality

Running May Lower Alzheimer's Mortality

Higher fruit intake, cholesterol-lowering drugs also associated with reduced risk.

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