Alzheimer’s Disease & Dementia

Cognitive Decline Delayed By Three Lifestyle Changes

Cognitive Decline Delayed By Three Lifestyle Changes

Three promising areas of future research in cognitive decline are blood pressure, cognitive training, and physical exercise.

Mild Cognitive Impairment Predicted By Dual Gait Task Training

Mild Cognitive Impairment Predicted By Dual Gait Task Training

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Dual task gait training is predictive of clinical progression of mild cognitive impairment leading to dementia.

Is Depression A Risk Factor Or a Prodromal Symptom of Dementia?

Is Depression A Risk Factor Or a Prodromal Symptom of Dementia?

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Depressive symptoms likely do not increase the risk of dementia.

Sleep Behavior, Irritability May Be an Early Symptom of Alzheimer's Disease

Sleep Behavior, Irritability May Be an Early Symptom of Alzheimer's Disease

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Neuropsychiatric symptoms, specifically sleep behavior and irritability, may be an early symptom of Alzheimer's dementia.

Serum Levels of Il-6 May Correlate With Cognitive Impairment in AD

Serum Levels of Il-6 May Correlate With Cognitive Impairment in AD

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Serum IL-6 levels may serve as biomarkers for Alzheimer's disease.

Increased Alzheimer's Disease Risk in Hospital-Treated Patients

Increased Alzheimer's Disease Risk in Hospital-Treated Patients

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Alzheimer's disease risk increases for hospitalized patients with shorter than a 5-year window.

Alzheimer's Disease More Associated With Vascular Risk Factors in Mid-Life Than Later Life

Alzheimer's Disease More Associated With Vascular Risk Factors in Mid-Life Than Later Life

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A history of 2 or more vascular risk factors was associated with a significantly higher rate of amyloid deposits on PET scans at last visit.

Silent Seizures May Affect Alzheimer's Pathology

Silent Seizures May Affect Alzheimer's Pathology

Early occult hippocampal hyperexcitability may contribute to the pathogenesis of Alzheimer's disease.

Alzheimer's Disease Not Protected by Post-Menopause Hormone Therapy

Alzheimer's Disease Not Protected by Post-Menopause Hormone Therapy

Women who use hormone therapy after menopause may not have a lower risk of developing Alzheimer's disease.

Benzodiazepines Increase Stroke Risk in Alzheimer's

Benzodiazepines Increase Stroke Risk in Alzheimer's

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As stroke is often detrimental for individuals with AD, these results warrant caution in BZDR use in this vulnerable population.

Sauna Use Lessens Likelihood of Dementia Diagnosis

Middle-aged men who frequent saunas are less likely to develop dementia.

Alzheimer's Disease Accelerated by Mild Brain Injury

Alzheimer's Disease Accelerated by Mild Brain Injury

Concussions may be associated with accelerated cortical thickness and memory decline in Alzheimer's disease-relevant areas.

Alzheimer's Disease is a Significant Risk Factor for Major Hip Fracture

Alzheimer's Disease is a Significant Risk Factor for Major Hip Fracture

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Cardiovascular disease, stroke, diabetes, hip and knee replacements, and both behavioral and mental disorders were also more common in the AD cohort.

Treatment for Alzheimer's Disease May Assist Tooth Repair

Treatment for Alzheimer's Disease May Assist Tooth Repair

Tideglusib, an Alzheimer's disease treatment, stimulates renewal of stem cells in the tooth pulp, enabling natural tooth repair.

Greater Weight Loss in Old Age Linked With MCI, Dementia

Greater Weight Loss in Old Age Linked With MCI, Dementia

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Normal cognitive function is associated with a more stable weight trajectory in older women.

Further Evidence Mediterranean Diet Ups Brain Health in Seniors

Further Evidence Mediterranean Diet Ups Brain Health in Seniors

Food in a Mediterranean diet protects against loss of brain volume in older populations.

Does Lithium Use Decrease Alzheimer's Risk?

Does Lithium Use Decrease Alzheimer's Risk?

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Researchers found that valproic acid increased the risk of Alzheimer's disease.

Hormone Therapy May Reduce Mortality Risk From Vascular Dementia

Hormone Therapy May Reduce Mortality Risk From Vascular Dementia

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Hormone therapy may reduce risk for death from vascular dementia in older women.

Link Between Antidementia Drug Use and Pneumonia Examined

Link Between Antidementia Drug Use and Pneumonia Examined

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The risk of developing pneumonia is higher among patients who use antidementia drugs.

Colonic Diverticular Disease May Increase Risk of Dementia

Colonic Diverticular Disease May Increase Risk of Dementia

In a large Taiwanese cohort, the overall rate of dementia was higher in the group with disease than in controls.

Increased Unsafe Med Scripts for Dual-System Users With Dementia

Increased Unsafe Med Scripts for Dual-System Users With Dementia

Rates of potentially unsafe medication are higher among veterans with dementia using VA-Medicare Part D system.

Amyloid Beta Deposits Can Affect The Heart in Alzheimer's

Amyloid Beta Deposits Can Affect The Heart in Alzheimer's

Amyloid deposits can lead to compromised myocardial function.

Saliva Test To Help Predict Alzheimer's Disease

Saliva Test To Help Predict Alzheimer's Disease

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Researchers found that higher amyloid-β protein levels in saliva were significantly associated with Alzheimer's patients.

Alzheimer's Trial: Solanezumab Fails Primary End Point

Alzheimer's Trial: Solanezumab Fails Primary End Point

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Eli Lilly's investigational Alzheimer's drug did not meet the primary end point in the phase 3 EXPEDITION3 trial.

New Data Shows Causal Link Between Vitamin D, Alzheimer's Risk

New Data Shows Causal Link Between Vitamin D, Alzheimer's Risk

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These findings, combined with those from prior observational research, provide a solid rationale for further randomized trials.

Drug Therapy Guidance Lacking for Sleep Disorders in Dementia

Drug Therapy Guidance Lacking for Sleep Disorders in Dementia

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A Cochrane systematic review found a clear lack of evidence for pharmacologic guidance of sleep problems in dementia.

MRI May Help Identify Lewy Body Dementia vs Alzheimer's

MRI May Help Identify Lewy Body Dementia vs Alzheimer's

Someone whose hippocampus stayed the same size was nearly 6 times more likely to develop Lewy body dementia.

Loneliness May Be a Precursor to Alzheimer's Disease

Loneliness May Be a Precursor to Alzheimer's Disease

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Recognition of self-reported symptoms that may appear at early onset of amyloid accumulation, such as loneliness, point to opportunities for preventive therapies.

Too Few Seniors Planning End-of-Life Care

Too Few Seniors Planning End-of-Life Care

Findings suggest that efforts to encourage more planning aren't working.

Probability of Dementia Higher in Men Receiving Androgen Deprivation Therapy

Probability of Dementia Higher in Men Receiving Androgen Deprivation Therapy

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The longer the duration of ADT, the greater the risk of dementia.

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