Alzheimer’s Disease & Dementia

Alzheimer's Disease Not Protected by Post-Menopause Hormone Therapy

Alzheimer's Disease Not Protected by Post-Menopause Hormone Therapy

Women who use hormone therapy after menopause may not have a lower risk of developing Alzheimer's disease.

Benzodiazepines Increase Stroke Risk in Alzheimer's

Benzodiazepines Increase Stroke Risk in Alzheimer's

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As stroke is often detrimental for individuals with AD, these results warrant caution in BZDR use in this vulnerable population.

VIDEO: Sauna Use Lessens Likelihood of Dementia Diagnosis

VIDEO: Sauna Use Lessens Likelihood of Dementia Diagnosis

Middle-aged men who frequent saunas are less likely to develop dementia.

Alzheimer's Disease Accelerated by Mild Brain Injury

Alzheimer's Disease Accelerated by Mild Brain Injury

Concussions may be associated with accelerated cortical thickness and memory decline in Alzheimer's disease-relevant areas.

Alzheimer's Disease is a Significant Risk Factor for Major Hip Fracture

Alzheimer's Disease is a Significant Risk Factor for Major Hip Fracture

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Cardiovascular disease, stroke, diabetes, hip and knee replacements, and both behavioral and mental disorders were also more common in the AD cohort.

Treatment for Alzheimer's Disease May Assist Tooth Repair

Treatment for Alzheimer's Disease May Assist Tooth Repair

Tideglusib, an Alzheimer's disease treatment, stimulates renewal of stem cells in the tooth pulp, enabling natural tooth repair.

Greater Weight Loss in Old Age Linked With MCI, Dementia

Greater Weight Loss in Old Age Linked With MCI, Dementia

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Normal cognitive function is associated with a more stable weight trajectory in older women.

Further Evidence Mediterranean Diet Ups Brain Health in Seniors

Further Evidence Mediterranean Diet Ups Brain Health in Seniors

Food in a Mediterranean diet protects against loss of brain volume in older populations.

Does Lithium Use Decrease Alzheimer's Risk?

Does Lithium Use Decrease Alzheimer's Risk?

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Researchers found that valproic acid increased the risk of Alzheimer's disease.

Hormone Therapy May Reduce Mortality Risk From Vascular Dementia

Hormone Therapy May Reduce Mortality Risk From Vascular Dementia

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Hormone therapy may reduce risk for death from vascular dementia in older women.

Link Between Antidementia Drug Use and Pneumonia Examined

Link Between Antidementia Drug Use and Pneumonia Examined

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The risk of developing pneumonia is higher among patients who use antidementia drugs.

Colonic Diverticular Disease May Increase Risk of Dementia

Colonic Diverticular Disease May Increase Risk of Dementia

In a large Taiwanese cohort, the overall rate of dementia was higher in the group with disease than in controls.

Increased Unsafe Med Scripts for Dual-System Users With Dementia

Increased Unsafe Med Scripts for Dual-System Users With Dementia

Rates of potentially unsafe medication are higher among veterans with dementia using VA-Medicare Part D system.

Amyloid Beta Deposits Can Affect The Heart in Alzheimer's

Amyloid Beta Deposits Can Affect The Heart in Alzheimer's

Amyloid deposits can lead to compromised myocardial function.

Saliva Test To Help Predict Alzheimer's Disease

Saliva Test To Help Predict Alzheimer's Disease

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Researchers found that higher amyloid-β protein levels in saliva were significantly associated with Alzheimer's patients.

Alzheimer's Trial: Solanezumab Fails Primary End Point

Alzheimer's Trial: Solanezumab Fails Primary End Point

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Eli Lilly's investigational Alzheimer's drug did not meet the primary end point in the phase 3 EXPEDITION3 trial.

New Data Shows Causal Link Between Vitamin D, Alzheimer's Risk

New Data Shows Causal Link Between Vitamin D, Alzheimer's Risk

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These findings, combined with those from prior observational research, provide a solid rationale for further randomized trials.

Drug Therapy Guidance Lacking for Sleep Disorders in Dementia

Drug Therapy Guidance Lacking for Sleep Disorders in Dementia

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A Cochrane systematic review found a clear lack of evidence for pharmacologic guidance of sleep problems in dementia.

MRI May Help Identify Lewy Body Dementia vs Alzheimer's

MRI May Help Identify Lewy Body Dementia vs Alzheimer's

Someone whose hippocampus stayed the same size was nearly 6 times more likely to develop Lewy body dementia.

Loneliness May Be a Precursor to Alzheimer's Disease

Loneliness May Be a Precursor to Alzheimer's Disease

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Recognition of self-reported symptoms that may appear at early onset of amyloid accumulation, such as loneliness, point to opportunities for preventive therapies.

Too Few Seniors Planning End-of-Life Care

Too Few Seniors Planning End-of-Life Care

Findings suggest that efforts to encourage more planning aren't working.

Probability of Dementia Higher in Men Receiving Androgen Deprivation Therapy

Probability of Dementia Higher in Men Receiving Androgen Deprivation Therapy

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The longer the duration of ADT, the greater the risk of dementia.

Midlife Hypertension and Late-life Neurocognitive Status

Midlife Hypertension and Late-life Neurocognitive Status

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The American Heart Association issues a scientific statement on the possible link between chronic arterial hypertension and cognitive impairment.

Gender-dependent Differences in Alzheimer Disease Diagnosis

Gender-dependent Differences in Alzheimer Disease Diagnosis

In 2016, an estimated 5.4 million US adults have Alzheimer disease.

High Thyroid Hormone Levels May Increase Dementia Risk

High Thyroid Hormone Levels May Increase Dementia Risk

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One hypothesis is that thyroid function affects dementia risk through nonvascular pathways.

Sundowning: Phenomenology, Pathophysiology, and Treatment Approaches

Sundowning: Phenomenology, Pathophysiology, and Treatment Approaches

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Sundowning is a complex multifactorial condition that has eluded rigorous understanding of its pathophysiological causes.

Alcohol Consumption and Alzheimer Disease: A Brief Update

Alcohol Consumption and Alzheimer Disease: A Brief Update

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Basic Research Findings for the Practicing Clinician

Late-onset Depression Associated with Elevated Dementia Risk

Late-onset Depression Associated with Elevated Dementia Risk

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Dementia risk was particularly elevated in patients with depression who had higher scores on cognitive tests at baseline.

How Does BMI Affect Alzheimer's Risk?

How Does BMI Affect Alzheimer's Risk?

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Those with lower BMI showed higher levels of beta-amyloid, closely tied to the onset of Alzheimer's disease.

How Continuity of Care Affects Hospitalizations, Health Care Costs in Dementia

How Continuity of Care Affects Hospitalizations, Health Care Costs in Dementia

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Analysis of over 1.4 million Medicare beneficiaries found that fragmented care led to an additional $567 million to $1.1 billion in health care spending.

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