Alcohol-Related Disorder

Significant variation in mortality trends in substance use disorders among US counties

Mortality rates decreased for alcohol use disorders, self-harm, and interpersonal violence between 1980 and 2014. Mortality rates for drug use disorders increased both nationally and in each county over the same period.

Interventions in Middle School Can Reduce Alcohol Misuse in Mexican American Adolescents

Interventions in Middle School Can Reduce Alcohol Misuse in Mexican American Adolescents

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Because even moderate reductions in adolescent drinking and alcohol use disorders have the potential to reduce short- and long-term public health harms, these findings support broad implementation of the program.

Mortality Rates for Substance Use Disorders, Intentional Injuries Vary Widely By County

Mortality Rates for Substance Use Disorders, Intentional Injuries Vary Widely By County

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Researchers calculated age-standardized mortality rates on a county level in the United States between 1980 and 2014, specifically examining rates for self-harm, interpersonal violence, alcohol use, and drug use.

Naltrexone More Effective for Alcohol Use Disorder in Nicotine Users

Naltrexone More Effective for Alcohol Use Disorder in Nicotine Users

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There has been much variability in the capacity for pharmacological treatments to help curb alcoholism, and the research community has remained interested in determining specific factors that may predict the efficacy of treatments such as naltrexone.

Fetal alcohol spectrum disorders likely to be vastly underdiagnosed in US

A multisite, cross-sectional study found a large mismatch between previously diagnosed fetal alcohol spectrum disorders and the actual prevalence of cases identified.

Drinkers Often Unsuccessful at Reducing Alcohol Use Despite Motivation

Drinkers Often Unsuccessful at Reducing Alcohol Use Despite Motivation

Not many high-risk individuals who are motivated to reduce alcohol comsumption are successful after 6 months.

Effects of Parents Supplying Alcohol to Adolescents

Effects of Parents Supplying Alcohol to Adolescents

Parents should be advised that this practice is associated with risk, both directly and indirectly through increased access to alcohol from other sources.

Varenicline Reduces Heavy Drinking, Cigarette Smoking in Men With Alcohol Use Disorder

Varenicline Reduces Heavy Drinking, Cigarette Smoking in Men With Alcohol Use Disorder

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Varenicline may have a role in the treatment of alcohol use disorder in men who smoke cigarettes.

Decrease in WHO Drinking Risk Level Significantly Reduces Alcohol Dependence

Decrease in WHO Drinking Risk Level Significantly Reduces Alcohol Dependence

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These results support the use of reductions in WHO drinking risk levels as an efficacy outcome in clinical trials.

High-Risk Drinking, Alcohol Use, and Alcohol Use Disorder Prevalence Increase

High-Risk Drinking, Alcohol Use, and Alcohol Use Disorder Prevalence Increase

Alcohol use and high-risk drinking were increased from 2001-2002 to 2012-2013.

Alcohol Addiction Leads to Biological Aging at a Cellular Level

Alcohol Addiction Leads to Biological Aging at a Cellular Level

According to a study presented at the Research Society on Alcoholism, heavy drinking is associated with biological aging at a cellular level.

Alcohol Consumption On the Rise Among Older Adults

Alcohol Consumption On the Rise Among Older Adults

Women over the age of 60 demonstrate an increased an upward trend in the prevalence of current drinking.

Untreated Psychotic Illness: Stemming the Tide

Untreated Psychotic Illness: Stemming the Tide

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Delays in treatment for psychosis can be associated with poorer outcomes.

Gender Differences in Alcohol Use Disappearing

Gender Differences in Alcohol Use Disappearing

Females are also closing the gender gap with regard to health problems associated with alcohol consumption.

Mechanism of Rapid Antidepressant Effect of Alcohol Elucidated

Mechanism of Rapid Antidepressant Effect of Alcohol Elucidated

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Acute exposure to ethanol led to antidepressant and anxiolytic behaviors in rodents for up to 24 hours.

Alcohol Use Disorder Drug Shows Promise

Alcohol Use Disorder Drug Shows Promise

CDC rank alcohol-attributable mortality as the third leading cause of preventable death in the United States.

Criticism of 12-Step Groups: Is It Warranted?

Criticism of 12-Step Groups: Is It Warranted?

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One topic of criticism is the relative dearth of scientific evidence regarding the efficacy of 12-step programs.

Histone Methyltransferase PRDM2 Implicated in Alcohol-dependent Behaviors

Histone Methyltransferase PRDM2 Implicated in Alcohol-dependent Behaviors

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Prdm2 contributes to key behaviors and long-term neuroadaptations associated with alcohol dependence

Female-specific CBT for Women Diagnosed With Alcohol Use Disorder

Female-specific CBT for Women Diagnosed With Alcohol Use Disorder

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Compared with men, women diagnosed with AUD have higher rates of premature death due to alcohol abuse.

Alcohol Consumption and Alzheimer Disease: A Brief Update

Alcohol Consumption and Alzheimer Disease: A Brief Update

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Basic Research Findings for the Practicing Clinician

Childhood ADHD and Adulthood Alcohol Problems: The Role of Emotional Impulsivity

Childhood ADHD and Adulthood Alcohol Problems: The Role of Emotional Impulsivity

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These findings are important, as CDC rank alcohol-attributable mortality as the third leading cause of preventable death in the United States.

Cognitive Performance in Patients With Alcohol Use Disorder

Cognitive Performance in Patients With Alcohol Use Disorder

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Researchers assessed social cognition and social problem solving abilities by employing ecologically valid scenario-based tests.

Drug Use in America: New Charts Illustrate Nationwide Trends

Drug Use in America: New Charts Illustrate Nationwide Trends

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The report also sheds light on the most significant predictors of substance abuse.

Interactive Effects of Genotype and Childhood Adversity on Alcohol Consumption

Interactive Effects of Genotype and Childhood Adversity on Alcohol Consumption

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Early life trauma interacts with FKBP5 genotype to predict heavy alcohol consumption in college students.

Striatal D1 and D2 Dopamine Receptor Activity Exert Opposite Influences on Alcohol Drinking

Striatal D1 and D2 Dopamine Receptor Activity Exert Opposite Influences on Alcohol Drinking

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Inhibition of D1 dopamine receptors in medium spiny neurons, or excitation of D1 dopamine receptors in medium spiny neurons, of the striatum, attenuated excessive alcohol consumption in mice.

LINKAGE Trial Ups Health Care Engagement In Addiction Treatment Patients

LINKAGE Trial Ups Health Care Engagement In Addiction Treatment Patients

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By taking better care of their health, researchers expect that LINKAGE participants will have better outcomes than usual care participants over time.

Following an Episode of Mania, Adults With Bipolar Disorder at Equal Risk for Depression or Anxiety

Following an Episode of Mania, Adults With Bipolar Disorder at Equal Risk for Depression or Anxiety

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Bipolar disorder (BD) is typically characterized by recurrent episodes of mania and depression, but the connection between BD and anxiety needs to be considered.

"Drunkorexia" Linked To Both Eating and Substance Use Disorders

"Drunkorexia" Linked To Both Eating and Substance Use Disorders

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Approximately 40% of American college students engage in binge drinking at least once in the past 2 weeks.

Differences in Alcohol Sales Laws Predict Heart Disease Outcomes

Differences in Alcohol Sales Laws Predict Heart Disease Outcomes

Alcohol consumption may reduce myocardial infarction odds, but up likelihood of atrial fibrillation.

Microstructure of Ethanol Consumption in Rodent Models of Alcoholism

Microstructure of Ethanol Consumption in Rodent Models of Alcoholism

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Comprehensive measurements of drinking behavior during episodes such as binge, abstinence, and relapse are essential to reveal the factors and mechanisms that underlie alcohol abuse and dependence.

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